采用发散型大分子单体法合成奇数代三嗪树枝状聚合物。
Synthesis of odd generation triazine dendrimers using a divergent, macromonomer approach.
机构信息
Department of Chemistry and the Laboratory for Molecular Simulation, Texas A&M University, College Station Texas 77843, USA.
出版信息
Org Lett. 2010 Mar 19;12(6):1148-51. doi: 10.1021/ol902669g.
Abstract
Using a macromonomer, first, third, and fifth generation triazine dendrimers can be prepared using a divergent approach. The nine-step process to the fifth generation target relies on an iterative two-reactions-per-generation strategy to yield the desired material in approximately 48% overall yield. This target displays 96 surface groups. NMR spectroscopy and mass spectrometry show that exceptionally narrow polydispersity is achieved using this strategy.
摘要
使用大分子单体，可以采用发散法制备第一代、第三代和第五代三嗪树状大分子。制备第五代目标物需要经过九步反应，这一过程依赖于每代两次的迭代策略，最终总收率约为 48%。该目标物显示出 96 个表面基团。核磁共振波谱和质谱表明，使用该策略可以实现非常窄的多分散性。
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