他汀类药物相关的重症肌无力肌无力：一例报告。
Statin-associated weakness in myasthenia gravis: a case report.
作者信息
Keogh Michael J, Findlay John M, Leach Simon, Bowen John
机构信息
Department of Stroke Medicine, United Lincolnshire Hospitals Trust, Lincoln County Hospital, Lincoln, LN2 5QY, UK.
出版信息
J Med Case Rep. 2010 Feb 20;4:61. doi: 10.1186/1752-1947-4-61.
INTRODUCTION
Myasthenia gravis is a commonly undiagnosed condition in the elderly. Statin medications can cause weakness and are linked to the development and deterioration of several autoimmune conditions, including myasthenia gravis.
CASE PRESENTATION
We report the case of a 60-year-old Caucasian man who presented with acute onset of dysarthria and dysphagia initially attributed to a brain stem stroke. Oculobulbar and limb weakness progressed until myasthenia gravis was diagnosed and treated, and until statin therapy was finally withdrawn.
CONCLUSION
Myasthenia gravis may be underappreciated as a cause of acute bulbar weakness among the elderly. Statin therapy appeared to have contributed to the weakness in our patient who was diagnosed with myasthenia gravis.
引言
重症肌无力在老年人中是一种常未被诊断出的病症。他汀类药物可导致肌无力，并与包括重症肌无力在内的多种自身免疫性疾病的发生和恶化有关。
病例报告
我们报告一例60岁白种男性病例，该患者最初表现为急性构音障碍和吞咽困难，最初被归因于脑干中风。眼球运动和肢体无力逐渐进展，直至重症肌无力被诊断并接受治疗，直至最终停用他汀类药物治疗。
结论
重症肌无力作为老年人急性延髓性肌无力的病因可能未得到充分认识。他汀类药物治疗似乎导致了我们这位被诊断为重症肌无力的患者出现肌无力症状。
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