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Statin-associated weakness in myasthenia gravis: a case report.

作者信息

Keogh Michael J, Findlay John M, Leach Simon, Bowen John

机构信息

Department of Stroke Medicine, United Lincolnshire Hospitals Trust, Lincoln County Hospital, Lincoln, LN2 5QY, UK.

出版信息

J Med Case Rep. 2010 Feb 20;4:61. doi: 10.1186/1752-1947-4-61.

Abstract

INTRODUCTION

Myasthenia gravis is a commonly undiagnosed condition in the elderly. Statin medications can cause weakness and are linked to the development and deterioration of several autoimmune conditions, including myasthenia gravis.

CASE PRESENTATION

We report the case of a 60-year-old Caucasian man who presented with acute onset of dysarthria and dysphagia initially attributed to a brain stem stroke. Oculobulbar and limb weakness progressed until myasthenia gravis was diagnosed and treated, and until statin therapy was finally withdrawn.

CONCLUSION

Myasthenia gravis may be underappreciated as a cause of acute bulbar weakness among the elderly. Statin therapy appeared to have contributed to the weakness in our patient who was diagnosed with myasthenia gravis.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cdf/2834677/c44cfe87c245/1752-1947-4-61-1.jpg

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