Department of Family Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Road, Taipei, Taiwan.
Arch Gerontol Geriatr. 2010 Feb;50 Suppl 1:S43-7. doi: 10.1016/S0167-4943(10)70012-1.
This study estimated the prevalence of frailty and identified the factors associated with frailty in Taiwan using data from the Survey of Health and Living Status of the Elderly. A nationwide probability sample including 2,238 individuals aged > or =65 years was interviewed in 2003. Based on the Cardiovascular Health Study conducted by Fried, five phenotypes of frailty were selected: poor appetite, exhaustion, low physical activity, poor walking ability, and poor twisting ability of fingers. Participants were classified as nonfrail, prefrail, and frail if they met 0, 1 or 2, and > or =3 criteria. The prevalences of nonfrailty, prefrailty, and frailty were 55.1%, 40.0%, and 4.9%, respectively. The prevalence of frailty increased with age and was greater in women. Frailty was associated with less education, no spouse, disability, higher rates of comorbid chronic diseases, depressive symptoms, and geriatric syndromes. Specific drug use, such as hypnotics, analgesics, herbal drugs, and parenteral fluid supplements was positively associated with frailty. The use of multivitamins, fish oil, and vitamin E was negatively associated with frailty. The prevalence of frailty is lower in Taiwan than in Western countries. Depressive symptoms, geriatric syndromes, and specific medication use are potential fields for frailty prevention in community-dwelling older adults.
本研究使用 2003 年“老年人健康与生活状况调查”的数据,估计了台湾地区衰弱的流行率,并确定了与衰弱相关的因素。该调查采用了全国概率抽样方法,包括 2238 名年龄≥65 岁的个体。基于 Fried 进行的心血管健康研究,选择了五种衰弱表型:食欲差、易疲劳、体力活动少、行走能力差和手指扭转能力差。如果符合 0、1 或 2 个及以上标准,则将参与者分为非衰弱、衰弱前期和衰弱。非衰弱、衰弱前期和衰弱的患病率分别为 55.1%、40.0%和 4.9%。衰弱的患病率随年龄增长而增加,女性患病率更高。衰弱与受教育程度较低、无配偶、残疾、慢性共病发生率较高、抑郁症状和老年综合征有关。特定药物的使用,如催眠药、镇痛药、草药和肠外补液补充剂,与衰弱呈正相关。使用多种维生素、鱼油和维生素 E 与衰弱呈负相关。台湾地区衰弱的患病率低于西方国家。抑郁症状、老年综合征和特定药物的使用是社区居住的老年人衰弱预防的潜在领域。