Department of Psychiatry, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 671 Hoes Lane, Piscataway, NJ 08854, USA.
J Clin Neurosci. 2010 Apr;17(4):539-40. doi: 10.1016/j.jocn.2009.09.001. Epub 2010 Feb 19.
Impulse control disorders, including pathological gambling, binge eating, compulsive shopping and hypersexual behaviors, have frequently been reported as a side effect of dopaminergic medications for Parkinson's disease (PD). Here we describe a patient with PD who developed an unusual manifestation of impulsive behaviors, including cigarette smoking, associated with an increase in dopamine agonist medication. We postulate this to be related to an overstimulation of mesolimbic dopamine receptors responsible for reward-seeking behaviors. Further research is needed to examine impulsive cigarette smoking in PD.
冲动控制障碍，包括病理性赌博、暴食、强迫性购物和性行为过度，经常被报道为帕金森病 (PD) 的多巴胺能药物的副作用。在这里，我们描述了一位 PD 患者，他出现了一种不寻常的冲动行为表现，包括吸烟，这与多巴胺激动剂药物的增加有关。我们推测这与负责寻求奖励行为的中脑边缘多巴胺受体的过度刺激有关。需要进一步研究来检查 PD 患者的冲动性吸烟行为。
