Takasaki Kenji, Umeki Hiroshi, Enatsu Kaori, Kumagami Hidetaka, Takahashi Haruo
Department of Otolaryngology-Head and Neck Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
Auris Nasus Larynx. 2010 Oct;37(5):644-7. doi: 10.1016/j.anl.2010.02.003. Epub 2010 Feb 20.
This study aimed to evaluate the pharyngeal pressure of a patient with, amyotrophic lateral sclerosis (ALS) before and after cricopharyngeal myotomy by high-resolution manometry (HRM) system.
A 60-year-old man with ALS underwent cricopharyngeal myotomy for his intractable, aspiration. The swallowing pressure along the velopharynx and upper esophagus was measured using, the HRM 1 month before and 3 months after the surgery.
Before cricopharyngeal myotomy, the maximum values of the resting UES pressure, the dry swallowing, pressures in the velopharyngeal muscle zone and in the UES zone were 89, 95, and 171 mmHg, respectively. After surgery, the maximum values of both the resting pressure and dry swallowing, pressure in the UES zone remarkably decreased to 21 and 75 mmHg, respectively.
This is the first report showing the effect of cricopharyngeal myotomy by demonstrating, the difference in the swallowing pressure along the velopharynx and upper esophagus before and after, the surgery in an ALS patient using this HRM system.
本研究旨在通过高分辨率测压（HRM）系统评估肌萎缩侧索硬化症（ALS）患者行环咽肌切开术前后的咽部压力。
一名60岁的ALS男性患者因顽固性误吸接受了环咽肌切开术。在手术前1个月和手术后3个月使用HRM测量沿软腭咽和上食管的吞咽压力。
环咽肌切开术前，静息UES压力、干吞咽时软腭咽肌区和UES区的压力最大值分别为89、95和171 mmHg。手术后，静息压力和干吞咽时UES区的压力最大值分别显著降至21和75 mmHg。
这是第一份报告，通过使用该HRM系统展示ALS患者手术前后沿软腭咽和上食管的吞咽压力差异，显示了环咽肌切开术的效果。
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