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本文引用的文献

1
Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription.调节环磷酸腺苷反应元件结合蛋白活性的转导器对促肾上腺皮质激素释放激素转录的影响。
Endocrinology. 2010 Mar;151(3):1109-18. doi: 10.1210/en.2009-0963. Epub 2010 Jan 15.
2
Mouse fertility is not dependent on the CREB coactivator Crtc1.小鼠的生育能力不依赖于CREB共激活因子Crtc1。
Nat Med. 2009 Sep;15(9):989-90; author reply 991. doi: 10.1038/nm0909-989.
3
A role for the CREB co-activator CRTC2 in the hypothalamic mechanisms linking glucose sensing with gene regulation.CREB 共激活因子 CRTC2 在将葡萄糖感知与基因调控联系起来的下丘脑机制中的作用。
EMBO Rep. 2009 Oct;10(10):1175-81. doi: 10.1038/embor.2009.177. Epub 2009 Aug 28.
4
CRTC2 (TORC2) contributes to the transcriptional response to fasting in the liver but is not required for the maintenance of glucose homeostasis.CRTC2（TORC2）有助于肝脏对禁食的转录反应，但对维持葡萄糖稳态并非必需。
Cell Metab. 2009 Jul;10(1):55-62. doi: 10.1016/j.cmet.2009.06.006.
5
Regulatory mechanisms underlying corticotropin-releasing factor gene expression in the hypothalamus.下丘脑促肾上腺皮质激素释放因子基因表达的调控机制。
Endocr J. 2009;56(3):335-44. doi: 10.1507/endocrj.k09e-075. Epub 2009 Apr 7.
6
TORC1 regulates activity-dependent CREB-target gene transcription and dendritic growth of developing cortical neurons.TORC1调节发育中皮质神经元的活性依赖型CREB靶基因转录和树突生长。
J Neurosci. 2009 Feb 25;29(8):2334-43. doi: 10.1523/JNEUROSCI.2296-08.2009.
7
The Creb1 coactivator Crtc1 is required for energy balance and fertility.Creb1共激活因子Crtc1是能量平衡和生育能力所必需的。
Nat Med. 2008 Oct;14(10):1112-7. doi: 10.1038/nm.1866. Epub 2008 Aug 31.
8
Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2.葡萄糖通过对TORC2的磷酸化调控来控制胰岛细胞中的CREB活性。
Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10161-6. doi: 10.1073/pnas.0800796105. Epub 2008 Jul 14.
9
Cyclic adenosine 3',5'-monophosphate responsive element binding protein phosphorylation is required but not sufficient for activation of corticotropin-releasing hormone transcription.环磷酸腺苷反应元件结合蛋白的磷酸化是促肾上腺皮质激素释放激素转录激活所必需的，但并不充分。
Endocrinology. 2008 Jul;149(7):3512-20. doi: 10.1210/en.2008-0052. Epub 2008 Mar 27.
10
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.胰岛素通过抑制辅激活因子TORC2来调节糖异生。
Nature. 2007 Sep 20;449(7160):366-9. doi: 10.1038/nature06128. Epub 2007 Sep 5.

TORC: a new twist on corticotropin-releasing hormone gene expression.

作者信息

Spencer Robert L, Weiser Michael J

机构信息

Department of Psychology and Neuroscience, University of Colorado, UCB 345, Boulder, Colorado 80309, USA.

出版信息

Endocrinology. 2010 Mar;151(3):855-8. doi: 10.1210/en.2009-1503.

DOI:10.1210/en.2009-1503
PMID:20172974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3213758/
Abstract
摘要