Department of Neurology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Oper Neurosurg (Hagerstown). 2010 Mar;66(suppl_1):ons-E121-ons-E123. doi: 10.1227/01.NEU.0000348560.85056.63.
To demonstrate that proton density weighted magnetic resonance imaging (MRI) at 3 T accomplishes delineation of the centre median (CM) complex from surrounding thalamic tissue and may improve targeting accuracy in stereotactic neurosurgery.
Five healthy subjects (1 man, 4 women; age range 22-35 years) underwent high-resolution MRI at 3 T with different imaging parameters in order to optimize the direct visualization of the CM.
In healthy subjects, the CM complex of the thalamus can be reliably contrasted on axially oriented slices by means of proton density weighted turbo-spin-echo MRI. An in-plane resolution of at least 0.6 x 0.6 mm2 is crucial at a slice thickness between 2 and 3 mm. Effective suppression of head motion is essential.
MRI-based delineation of the CM could have therapeutic potential to facilitate target determination for neuromodulation in stereotactic neurosurgery.
证明 3T 质子密度加权磁共振成像（MRI）能够从周围丘脑组织中描绘出中央正中（CM）复合体，并可能提高立体定向神经外科手术的靶向准确性。
5 名健康受试者（1 名男性，4 名女性；年龄 22-35 岁）在 3T 下进行高分辨率 MRI，使用不同的成像参数以优化 CM 的直接可视化。
在健康受试者中，通过质子密度加权涡轮自旋回波 MRI，可以在轴位切片上可靠地对比丘脑的 CM 复合体。在 2 到 3 毫米的切片厚度下，平面分辨率至少为 0.6 x 0.6 毫米 2 至关重要。有效抑制头部运动至关重要。
基于 MRI 的 CM 描绘可能具有治疗潜力，有助于确定立体定向神经外科中神经调节的目标。
