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儿童多中心复发性腮腺多形性腺瘤。

Multicentric recurrent parotid pleomorphic adenoma in a child.

机构信息

General and University Hospital, ENT Department, Valencia, Spain.

出版信息

Med Oral Patol Oral Cir Bucal. 2010 Sep 1;15(5):e743-5. doi: 10.4317/medoral.15.e743.

Abstract

Mixed tumours of the parotid gland are rare in childhood and recurrence of this tumour is infrequent. Some authors report a higher rate of recurrence with some histological subtypes, like hypocellular variant. Female sex and young age at initial treatment are also risk factor for recurrence. Also the first surgical treatment, tumour enucleation or parotidectomy, has been implicated as a cause for recurrence. We present a case of a multicentric doubly recurrent parotid pleomorphic adenoma, 7 and 14 years after tumour enucleation, in a 9-year-old child. All the nodules resected showed the hypocellular variant of pleomorphic adenoma. We consider the relationships between the choice of treatment, the histologic subtypes of pleomorphic adenomas and multifocal tumours and recurrence. In this case, we believe the recurrence was related to surgical enucleation previously performed and the hypocellular histological subtype. We conclude that tumour enucleation is a risk factor for recurrence and total parotidectomy is the treatment of choice for pleomorphic parotid adenoma also in childhood.

摘要

腮腺混合瘤在儿童中较为罕见,且该肿瘤复发率较低。一些作者报告称,某些组织学亚型(如低细胞型)的复发率更高,如女性性别和初始治疗时的年轻年龄也是复发的危险因素。此外,首次手术治疗,如肿瘤剜除术或腮腺切除术,也被认为是复发的原因。我们报告了一例 9 岁儿童腮腺多中心复发性多形性腺瘤,在肿瘤剜除术后 7 年和 14 年分别复发。切除的所有结节均显示多形性腺瘤的低细胞型。我们考虑了治疗选择、多形性腺瘤的组织学亚型与多灶性肿瘤和复发之间的关系。在这种情况下,我们认为复发与之前进行的手术剜除术和低细胞组织学亚型有关。我们得出结论,肿瘤剜除术是复发的危险因素,对于儿童多形性腺瘤腮腺,腮腺全切除术也是首选治疗方法。

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