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巴西某中心对腭部多形性腺瘤(PPA)复发10年后的手术治疗——病例报告

Surgical Management of Palatal Pleomorphic Adenoma (PPA) Recurrence After 10 years, Treated at a Brazilian Center - A Case Report.

作者信息

De Lima Flávio Fidêncio, Bezerra Catarina Pires, Rocha André Caroli, Martins Ivan Solani, Bernaola-Paredes Wilber Edison

机构信息

Department of Implantodontics, School of Dentistry, Paulist University, Sao Paulo, Brazil.

Department of Dentistry and Restoration, School of Dentistry, Paulist University, Sao Paulo, Brazil.

出版信息

Ann Maxillofac Surg. 2020 Jul-Dec;10(2):533-536. doi: 10.4103/ams.ams_107_20. Epub 2020 Dec 23.

Abstract

Pleomorphic adenoma, considered the most frequent benign mixed neoplasm of the minor salivary glands, occurs mainly in the region of the hard palate, with slight predilection in females and peak of incidence between the third and fifth decades of life. An increase in recurrence rates has been associated with the histopathological variants of the tumor, cellular characteristics, stroma, and capsule rupture during surgical removal of the lesion. The present case report aims to describe the surgical approach performed on the patient, a 45-year-old woman with a recurrent Pleomorphic Adenoma (PA) in the region of the hard palate on the right side, 10 years after initial enucleation of the lesion; her main complaint was an increase in volume in the palatal region. After extensive local surgical excision of the tumor and 2 years of follow-up, there were no signs of recurrence. Computed tomography and a correct histopathological diagnosis are essential to enable the establishment of an appropriate surgical treatment, with the purpose of achieving complete removal of the lesion, with wide surgical margins, including the lining mucosa and the underlying periosteum, as described in the present case.

摘要

多形性腺瘤被认为是小唾液腺最常见的良性混合性肿瘤,主要发生在硬腭区域,女性略多,发病高峰在30至50岁之间。肿瘤的组织病理学变异、细胞特征、间质以及手术切除病变时的包膜破裂与复发率增加有关。本病例报告旨在描述对一名45岁女性患者采取的手术方法,该患者右侧硬腭区域复发性多形性腺瘤(PA),最初摘除病变10年后出现;她的主要主诉是腭部区域肿物增大。在对肿瘤进行广泛的局部手术切除并随访2年后,未见复发迹象。计算机断层扫描和正确的组织病理学诊断对于确定合适的手术治疗至关重要,目的是实现病变的完全切除,切缘要宽,包括衬里黏膜和下方的骨膜,如本病例所述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd7a/7944004/55b9fe3cd60d/AMS-10-533-g001.jpg

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