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高氧增加自发性高血压大鼠(SHR)的盐摄入量。

Hyperoxia increases salt intake in spontaneously hypertensive rats (SHR).

作者信息

Behm R, Rückborn K, Franz U

机构信息

Department of Physiology, Wilhelm-Pieck-University, Rostock, Germany.

出版信息

Physiol Behav. 1991 Jan;49(1):165-7. doi: 10.1016/0031-9384(91)90250-r.

DOI:10.1016/0031-9384(91)90250-r
PMID:2017472
Abstract

The effect of normobaric hyperoxia on voluntary salt intake was investigated in 20 sham-operated and 11 carotid body-denervated SHR. While in sham-operated SHR the saline intake was enhanced during the whole hyperoxic period, the carotid body-denervated rats showed an increase in salt appetite only on the second and third day of hyperoxia. Water intake was not significantly different in sham-operated and carotid body-denervated SHR. These findings, together with our previous results, suggest that chemoreceptor activity determines salt appetite but not water intake in SHR.

摘要

在20只假手术的自发性高血压大鼠(SHR)和11只颈动脉体去神经支配的SHR中,研究了常压高氧对自愿盐摄入的影响。在整个高氧期间,假手术的SHR的盐水摄入量增加,而颈动脉体去神经支配的大鼠仅在高氧的第二天和第三天出现盐食欲增加。假手术和颈动脉体去神经支配的SHR的水摄入量没有显著差异。这些发现与我们之前的结果一起表明,化学感受器活动决定了SHR的盐食欲,但不决定其水摄入量。

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1
Hyperoxia increases salt intake in spontaneously hypertensive rats (SHR).高氧增加自发性高血压大鼠(SHR)的盐摄入量。
Physiol Behav. 1991 Jan;49(1):165-7. doi: 10.1016/0031-9384(91)90250-r.
2
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Hypertension is critically dependent on the carotid body input in the spontaneously hypertensive rat.高血压在很大程度上依赖于自发性高血压大鼠颈动脉体的输入。
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