Kizilkan Nese, Davutoglu Vedat, Erbagci Hulya, Karagoz Alper, Akcay Murat, Sari Ibrahim, Ercan Suleyman, Dogan Adnan
Department of Anatomy, Faculty of Medicine, School of Medicine, Gaziantep University, Gaziantep TR 27310, Turkey.
Saudi Med J. 2010 Feb;31(2):153-7.
To evaluate the usefulness of examining the coronary sinus (CS) anatomic diameter as an additional surrogate marker of severity in chronic rheumatic valve disease (RVD).
In this cross-sectional observational study, we echocardiographically analyzed 88 patients with RVD, and 104 normal subjects in the Department of Cardiology, Gaziantep University Medical Faculty, Gaziantep, Turkey between February 2007 and April 2007. Echocardiographically all valve regurgitation, stenosis, left ventricular function, left/right atrial volume, and pulmonary artery pressure were obtained. Coronary sinus was assessed as a sonolucency in the posterior atrioventricular groove.
Strong positive correlation was present between CS measurements and mitral mean gradient, mitral and tricuspid regurgitation grade, tricuspid stenosis gradient, pulmonary artery systolic pressure, left and right atrial volume, and New York Heart Association class. A statistically negative correlation was present between CS measurements and mitral valve area and ejection fraction. Only the mitral valve area, tricuspid regurgitation grade, and the right atrial volume were predictors of body surface area adjusted mean CS dilatation.
In this preliminary study, we showed that echocardiographic assessment of dilated CS may provide useful additional information in predicting the severity of mitral/tricuspid RVD. Findings of this study needs to be confirmed in further studies.
评估检测冠状窦(CS)解剖直径作为慢性风湿性瓣膜病(RVD)严重程度的额外替代标志物的实用性。
在这项横断面观察性研究中,我们于2007年2月至2007年4月期间,对土耳其加济安泰普大学医学院心脏病科的88例RVD患者和104例正常受试者进行了超声心动图分析。通过超声心动图获取所有瓣膜反流、狭窄、左心室功能、左/右心房容积和肺动脉压力。将冠状窦评估为房室后沟中的无回声区。
CS测量值与二尖瓣平均压差、二尖瓣和三尖瓣反流分级、三尖瓣狭窄压差、肺动脉收缩压、左心房和右心房容积以及纽约心脏协会分级之间存在强正相关。CS测量值与二尖瓣面积和射血分数之间存在统计学负相关。只有二尖瓣面积、三尖瓣反流分级和右心房容积是体表面积校正后平均CS扩张的预测因素。
在这项初步研究中,我们表明超声心动图评估扩张的CS可能为预测二尖瓣/三尖瓣RVD的严重程度提供有用的额外信息。本研究结果需要在进一步研究中得到证实。