Division of Lung Diseases, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Am J Perinatol. 2010 Aug;27(7):549-58. doi: 10.1055/s-0030-1248942. Epub 2010 Feb 19.
A marked reduction in infant mortality due to respiratory distress syndrome (RDS) has been reported in previous studies; however, deaths due to RDS are still more common in black infants than white infants. Because advances in respiratory care may have impacted non-RDS respiratory causes of infant mortality as well, the objective of this study was to determine if specific and total non-RDS respiratory causes of infant mortality have changed over time, and if health disparities exist. We analyzed and compared infant deaths due to RDS and other respiratory diseases from 1980 to 2005 in the United States and evaluated outcomes by race and gender. Infant mortality due to non-RDS causes declined more than twofold over this time frame, but not as dramatically as the fivefold decline in RDS deaths. Black compared with white infants had twice the mortality rate due to non-RDS respiratory causes. The most common non-RDS respiratory cause of infant mortality was due to congenital malformations of the respiratory tract, which did not change dramatically over the 25 years studied.
先前的研究报告指出，由于呼吸窘迫综合征（RDS），婴儿死亡率显著降低；然而，死于 RDS 的黑人婴儿仍比白人婴儿多。由于呼吸护理方面的进步可能也影响了非 RDS 导致的婴儿呼吸死亡原因，因此本研究的目的是确定非 RDS 导致的婴儿呼吸死亡的具体原因和总体原因是否随时间而变化，以及是否存在健康差异。我们分析并比较了 1980 年至 2005 年美国因 RDS 和其他呼吸疾病导致的婴儿死亡，并按种族和性别评估了结果。在此期间，非 RDS 导致的婴儿死亡率下降了两倍多，但远不及 RDS 死亡人数下降的五倍。与白人婴儿相比，黑人婴儿因非 RDS 呼吸道疾病导致的死亡率是其两倍。非 RDS 导致婴儿死亡的最常见原因是呼吸道先天性畸形，在 25 年的研究中并没有显著变化。
