Zahn T P, Nurnberger J I, Berrettini W H, Robinson T N
Laboratory of Psychology and Psychopathology, National Institute of Mental Health, Bethesda, MD 20892.
Psychiatry Res. 1991 Jan;36(1):99-110. doi: 10.1016/0165-1781(91)90121-5.
Correlations between electrodermal and heart rate indices of autonomic nervous system (ANS) activity and measures of state and trait anxiety were examined in 22 high-risk subjects, who had a parent with bipolar affective disorder, and in controls. Relatively consistent and significant correlations between anxiety and ANS "arousal" at rest and under stress were found in high-risk subjects, but not in controls. Relationships between electrodermal laterality and anxiety, and between electrodermal activity and heart rate, were also observed only in the high-risk group. The data suggest a unique concordance between various manifestations of anxiety in high-risk persons which may effectively increase the salience of stressful events and the sensitization to stress.
在22名高危受试者（其父母患有双相情感障碍）和对照组中，研究了自主神经系统（ANS）活动的皮肤电和心率指标与状态焦虑和特质焦虑测量值之间的相关性。在高危受试者中发现焦虑与静息和应激状态下的ANS“唤醒”之间存在相对一致且显著的相关性，但在对照组中未发现。仅在高危组中还观察到皮肤电侧化与焦虑之间以及皮肤电活动与心率之间的关系。数据表明高危人群中焦虑的各种表现之间存在独特的一致性，这可能有效地增加应激事件的显著性以及对应激的敏感性。
