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腹腔镜胆囊切除术后主要胆管损伤的重建

Reconstruction of major bile duct injuries after laparoscopic cholecystectomy.

作者信息

Holte Kathrine, Bardram Linda, Wettergren André, Rasmussen Allan

机构信息

Rigshospitalet, Department of Surgery and Transplantation.

出版信息

Dan Med Bull. 2010 Feb;57(2):A4135.

Abstract

INTRODUCTION

Bile duct injury (BDI) after cholecystectomy remains a serious complication with major implications for patient outcome. For most major BDIs, the recommended method of repair is a hepaticojejunostomy (HJ). We conducted a retrospective review aiming to examine the perioperative and the long-term outcome after reconstructive HJ at our institution.

MATERIAL AND METHODS

Retrospective review of 41 consecutive patients with BDI sustained during cholecystectomy and subsequently managed with a HJ. The patients were referred to a tertiary hepato-biliary centre during a 15-year period (1994-2008).

RESULTS

A total of 32 cases (78%) were reconstructed within two weeks of injury. While 14 patients (34%) suffered perioperative complications, 22 patients (54%) had a complication-free short as well as long-term outcome. Within a median follow-up period of 9.2 years, ten patients (24%) developed biliary strictures requiring percutaneous dilatation and/or further surgery. Three patients had further segmental hepatectomies and one patient developed secondary biliary cirrhosis necessitating orthotopic liver transplantation. No association was found between timing of repair or level of injury and outcome.

CONCLUSION

Early specialist repair may result in acceptable short as well as long-term outcome; however, the morbidity of reconstructive biliary surgery remains high--particularly in the context of patient expectations before laparoscopic cholecystectomy.

摘要

引言

胆囊切除术后胆管损伤(BDI)仍然是一种严重的并发症,对患者的预后有重大影响。对于大多数严重的BDI,推荐的修复方法是肝空肠吻合术(HJ)。我们进行了一项回顾性研究,旨在探讨我院行重建性HJ术后的围手术期及长期预后。

材料与方法

回顾性分析41例胆囊切除术中发生BDI并随后接受HJ治疗的连续患者。这些患者在15年期间(1994 - 2008年)被转诊至一家三级肝胆中心。

结果

共有32例(78%)在损伤后两周内进行了重建。14例患者(34%)发生围手术期并发症,22例患者(54%)短期及长期预后均无并发症。在中位随访期9.2年时,10例患者(24%)出现胆管狭窄,需要经皮扩张和/或进一步手术。3例患者接受了进一步的肝段切除术,1例患者发展为继发性胆汁性肝硬化,需要进行原位肝移植。未发现修复时间或损伤部位与预后之间存在关联。

结论

早期专科修复可能导致可接受的短期及长期预后;然而,重建性胆管手术的发病率仍然很高——特别是在腹腔镜胆囊切除术之前患者期望的背景下。

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