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鼻炎和鼻窦炎。

Rhinitis and sinusitis.

机构信息

Allergy and Immunology Unit, Section of Pulmonary, Critical Care Allergy and Immunologic Diseases, Department of Internal Medicine, Center for Human Genomics and Personalized Medicine Research, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

出版信息

J Allergy Clin Immunol. 2010 Feb;125(2 Suppl 2):S103-15. doi: 10.1016/j.jaci.2009.12.989.

Abstract

Rhinitis and sinusitis are among the most common medical conditions and are frequently associated. In Western societies an estimated 10% to 25% of the population have allergic rhinitis, with 30 to 60 million persons being affected annually in the United States. It is estimated that sinusitis affects 31 million patients annually in the United States. Both rhinitis and sinusitis can significantly decrease quality of life, aggravate comorbid conditions, and require significant direct medical expenditures. Both conditions also create even greater indirect costs to society by causing lost work and school days and reduced workplace productivity and school learning. Management of allergic rhinitis involves avoidance, many pharmacologic options, and, in appropriately selected patients, allergen immunotherapy. Various types of nonallergic rhinitis are treated with avoidance measures and a more limited repertoire of medications. For purposes of this review, sinusitis and rhinosinusitis are synonymous terms. An acute upper respiratory illness of less than approximately 7 days' duration is most commonly caused by viral illness (viral rhinosinusitis), whereas acute bacterial sinusitis becomes more likely beyond 7 to 10 days. Although the mainstay of management of acute bacterial sinusitis is antibiotics, treatment of chronic sinusitis is less straightforward because only some chronic sinusitis cases have an infectious basis. Chronic rhinosinusitis (CRS) has been subdivided into 3 types, namely CRS without nasal polyps, CRS with nasal polyps, and allergic fungal rhinosinusitis. Depending on the type of CRS present, a variety of medical and surgical approaches might be required.

摘要

鼻炎和鼻窦炎是最常见的医学病症之一,且常同时发生。在西方社会,据估计有 10%至 25%的人口患有过敏性鼻炎,每年有 3000 万至 6000 万人受其影响。据估计,每年有 3100 万美国人患有鼻窦炎。鼻炎和鼻窦炎都会显著降低生活质量,加重并存病症,并需要大量直接医疗支出。这两种病症还会通过导致旷工和缺课以及降低工作场所生产力和学校学习效率给社会造成更大的间接成本。过敏性鼻炎的治疗包括避免接触过敏原、多种药物选择,以及在适当选择的患者中进行过敏原免疫治疗。各种非过敏性鼻炎则通过避免接触和更有限的药物治疗。出于本综述的目的,鼻窦炎和鼻-鼻窦炎是同义术语。持续时间少于约 7 天的急性上呼吸道疾病最常见的病因是病毒性疾病(病毒性鼻-鼻窦炎),而急性细菌性鼻窦炎在 7 至 10 天后更有可能发生。尽管急性细菌性鼻窦炎的主要治疗方法是抗生素,但慢性鼻窦炎的治疗则不那么简单,因为只有部分慢性鼻窦炎病例具有感染基础。慢性鼻-鼻窦炎(CRS)已分为 3 种类型,即无鼻息肉的 CRS、有鼻息肉的 CRS 和变应性真菌性鼻-鼻窦炎。根据存在的 CRS 类型,可能需要多种医疗和手术方法。

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