Hell K
Department of Surgery, University of Basel, Switzerland.
Rev Infect Dis. 1991 Jan-Feb;13 Suppl 2:S164-9. doi: 10.1093/clinids/13.supplement_2.s164.
Prompt administration of antibiotics is of the utmost importance in the treatment of wounds inflicted during a war or disaster. A single injection of a broad-spectrum drug with a long half-life should be given prophylactically to personnel on the battlefield to provide bactericidal coverage from the earliest possible moment after injury occurs. The antibiotic must remain effective at least throughout the period of transport to hospital and surgery. Use of antimicrobial agents will never replace careful surgical debridement, and these drugs should be used again later only if a bacterial infection develops. Other considerations include the choice of a drug that penetrates tissue thoroughly, is simple to store and administer, is easily available, and is cost effective.
在战争或灾难中受伤的伤口治疗中，及时使用抗生素至关重要。应在战场上对人员预防性地单次注射一种半衰期长的广谱药物，以便在受伤后尽早提供杀菌覆盖。抗生素必须至少在运输到医院和手术的整个期间保持有效。使用抗菌药物绝不能取代仔细的外科清创术，并且只有在发生细菌感染时才应在之后再次使用这些药物。其他需要考虑的因素包括选择一种能彻底穿透组织、易于储存和给药、容易获得且具有成本效益的药物。
