Kim Michelle M, Barnato Amber E, Angus Derek C, Fleisher Lee A, Kahn Jeremy M
Department of Health Care Management and Economics, Wharton School of Business, University of Pennsylvania, Philadelphia, PA 19104, USA.
Arch Intern Med. 2010 Feb 22;170(4):369-76. doi: 10.1001/archinternmed.2009.521.
Critically ill patients are medically complex and may benefit from a multidisciplinary approach to care.
We conducted a population-based retrospective cohort study of medical patients admitted to Pennsylvania acute care hospitals (N = 169) from July 1, 2004, to June 30, 2006, linking a statewide hospital organizational survey to hospital discharge data. Multivariate logistic regression was used to determine the independent relationship between daily multidisciplinary rounds and 30-day mortality.
A total of 112 hospitals and 107 324 patients were included in the final analysis. Overall 30-day mortality was 18.3%. After adjusting for patient and hospital characteristics, multidisciplinary care was associated with significant reductions in the odds of death (odds ratio [OR], 0.84; 95% confidence interval [CI], 0.76-0.93 [P = .001]). When stratifying by intensivist physician staffing, the lowest odds of death were in intensive care units (ICUs) with high-intensity physician staffing and multidisciplinary care teams (OR, 0.78; 95% CI, 0.68-0.89 [P < .001]), followed by ICUs with low-intensity physician staffing and multidisciplinary care teams (OR, 0.88; 95% CI, 0.79-0.97 [P = .01]), compared with hospitals with low-intensity physician staffing but without multidisciplinary care teams. The effects of multidisciplinary care were consistent across key subgroups including patients with sepsis, patients requiring invasive mechanical ventilation, and patients in the highest quartile of severity of illness.
Daily rounds by a multidisciplinary team are associated with lower mortality among medical ICU patients. The survival benefit of intensivist physician staffing is in part explained by the presence of multidisciplinary teams in high-intensity physician-staffed ICUs.
重症患者病情复杂,多学科综合治疗模式可能对其治疗有益。
我们进行了一项基于人群的回顾性队列研究,研究对象为2004年7月1日至2006年6月30日期间入住宾夕法尼亚州急症医院的内科患者(N = 169),将全州医院组织调查与医院出院数据相联系。采用多因素逻辑回归分析确定每日多学科查房与30天死亡率之间的独立关系。
最终分析纳入了112家医院的107324例患者。总体30天死亡率为18.3%。在对患者和医院特征进行调整后,多学科综合治疗与死亡几率显著降低相关(优势比[OR],0.84;95%置信区间[CI],0.76 - 0.93 [P = 0.001])。按重症医学科医生配备情况分层时,死亡几率最低的是配备高强度医生且有多学科综合治疗团队的重症监护病房(ICU)(OR,0.78;95% CI,0.68 - 0.89 [P < 0.001]),其次是配备低强度医生且有多学科综合治疗团队的ICU(OR,0.88;95% CI,0.79 - 0.97 [P = 0.01]),相比之下,配备低强度医生但没有多学科综合治疗团队的医院死亡几率较高。多学科综合治疗的效果在包括脓毒症患者、需要有创机械通气的患者以及疾病严重程度处于最高四分位数的患者等关键亚组中是一致的。
多学科团队每日查房与内科ICU患者较低的死亡率相关。重症医学科医生配备带来的生存获益部分可由配备高强度医生的ICU中多学科团队的存在来解释。