Arnold S R, Ford-Jones E L
Division of Infectious Diseases, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario.
Paediatr Child Health. 2000 Nov;5(8):463-9. doi: 10.1093/pch/5.8.463.
Although congenital syphilis is a rare disease in Canada, infected infants may experience severe sequelae, including cerebral palsy, hydrocephalus, sensorineural hearing loss and musculoskeletal deformity. Timely treatment of congenital syphilis during pregnancy may prevent all of the above sequelae. However, the diagnosis of suspected cases and management of congenital syphilis may be confusing, and the potential for severe disability is high when cases are missed. The present review provides assistance to practitioners in the diagnosis of suspected cases and management of children with presumed or confirmed infection.
尽管先天性梅毒在加拿大是一种罕见疾病,但受感染的婴儿可能会出现严重的后遗症,包括脑瘫、脑积水、感音神经性听力损失和肌肉骨骼畸形。孕期及时治疗先天性梅毒可预防上述所有后遗症。然而,先天性梅毒疑似病例的诊断和管理可能令人困惑,漏诊时出现严重残疾的可能性很高。本综述为从业者诊断疑似病例以及管理疑似或确诊感染儿童提供帮助。