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The value of penicillin alone in the prevention and treatment of congenital syphilis.青霉素在先天性梅毒防治中的单独应用价值。
Acta Derm Venereol Suppl (Stockh). 1950;31(Suppl. 24):60-87.
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Syphilis: review with emphasis on clinical, epidemiologic, and some biologic features.梅毒:重点关注临床、流行病学及一些生物学特征的综述。
Clin Microbiol Rev. 1999 Apr;12(2):187-209. doi: 10.1128/CMR.12.2.187.
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Maternal syphilis and vertical perinatal transmission of human immunodeficiency virus type-1 infection.孕产妇梅毒与1型人类免疫缺陷病毒的垂直围产期传播
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Contribution of long-bone radiographs to the management of congenital syphilis in the newborn infant.长骨X线片在新生儿先天性梅毒管理中的作用
Arch Pediatr Adolesc Med. 1998 Apr;152(4):353-7. doi: 10.1001/archpedi.152.4.353.
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MMWR Recomm Rep. 1998 Jan 23;47(RR-1):1-111.
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Problems in the current case definitions of congenital syphilis.
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Maternal and congenital syphilis in Brooklyn, NY. Epidemiology, transmission, and diagnosis.纽约布鲁克林区的母婴梅毒和先天性梅毒。流行病学、传播及诊断
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Treatment of syphilis, 1993.
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Laboratory diagnosis and interpretation of tests for syphilis.梅毒检测的实验室诊断与解读
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先天性梅毒:诊断与管理指南

Congenital syphilis: A guide to diagnosis and management.

作者信息

Arnold S R, Ford-Jones E L

机构信息

Division of Infectious Diseases, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario.

出版信息

Paediatr Child Health. 2000 Nov;5(8):463-9. doi: 10.1093/pch/5.8.463.

DOI:10.1093/pch/5.8.463
PMID:20177559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2819963/
Abstract

Although congenital syphilis is a rare disease in Canada, infected infants may experience severe sequelae, including cerebral palsy, hydrocephalus, sensorineural hearing loss and musculoskeletal deformity. Timely treatment of congenital syphilis during pregnancy may prevent all of the above sequelae. However, the diagnosis of suspected cases and management of congenital syphilis may be confusing, and the potential for severe disability is high when cases are missed. The present review provides assistance to practitioners in the diagnosis of suspected cases and management of children with presumed or confirmed infection.

摘要

尽管先天性梅毒在加拿大是一种罕见疾病,但受感染的婴儿可能会出现严重的后遗症,包括脑瘫、脑积水、感音神经性听力损失和肌肉骨骼畸形。孕期及时治疗先天性梅毒可预防上述所有后遗症。然而,先天性梅毒疑似病例的诊断和管理可能令人困惑,漏诊时出现严重残疾的可能性很高。本综述为从业者诊断疑似病例以及管理疑似或确诊感染儿童提供帮助。