Supronowicz Łukasz, Rogalska Magdalena
Department of Infectious Diseases and Hepatology, Medical University of Bialystok, Poland.
Clin Exp Hepatol. 2024 Mar;10(1):9-13. doi: 10.5114/ceh.2024.136235. Epub 2024 Mar 12.
Syphilis is a sexually transmitted multisystemic disease known as "the great imitator" due to its variable presentations. Despite being preventable and curable, it still constitutes a major health problem. Hepatic manifestation of syphilis is usually mild cholestatic liver injury but in very rare cases can become fulminant. Moreover, syphilitic hepatitis, known for several decades, is considered rare but is probably under-diagnosed. Given the significant morbidity associated with a missed diagnosis, syphilitic hepatitis should be taken into account as an element of differential diagnosis in patients with unexplained elevation of liver enzymes.
梅毒是一种性传播的多系统疾病，因其表现多样而被称为“伟大的模仿者”。尽管它是可预防和可治愈的，但仍然是一个主要的健康问题。梅毒的肝脏表现通常为轻度胆汁淤积性肝损伤，但在极少数情况下可能会发展为暴发性肝损伤。此外，梅毒肝炎虽已被认识数十年，但被认为较为罕见，可能存在诊断不足的情况。鉴于漏诊会带来严重的发病率，对于不明原因肝酶升高的患者，应将梅毒肝炎作为鉴别诊断的一个因素加以考虑。
