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静脉注射碳氢化合物后的肺损伤。

Pulmonary injury after intravenous hydrocarbon injection.

作者信息

Guerguerian A M, Lacroix J

机构信息

Pediatric Intensive Care Unit, Departments of Pediatrics, Sainte-Justine Hospital, Université de Montréal, Montréal, Québec.

出版信息

Paediatr Child Health. 2000 Nov;5(8):471-2. doi: 10.1093/pch/5.8.471.

Abstract

This report describes the case of a young man in whom an intravenous injection of a hydrocarbon led to reversible pulmonary edema. An 18-year-old male presented with chest pain, a cough and progressive dyspnea at a multidisciplinary paediatric intensive care unit in a tertiary care university hospital. Six hours after oxygen was given, blood gases were pH 7.16, partial pressure of carbon dioxide 43 torr (5.7 kPa), partial pressure of arterial oxygen 149 torr (19.9 kPa) and bicarbonate concentration 15 mEq/L. A chest radiograph suggested pulmonary edema. On day 3, the patient stated that he had injected himself with Varsol (Imperial Oil, Canada) - a mixture of straight and branched-chain hydrocarbons, naphthenes and alkyl derivatives of benzene - several hours before his admission. On day 5, the patient's respiratory rate returned to 20 breaths/min, and his chest radiograph was normal by day 7. The present case report suggests that the intravenous injection of hydrocarbons may lead to reversible pulmonary injury.

摘要

本报告描述了一名年轻男子的病例,其静脉注射碳氢化合物后出现可逆性肺水肿。一名18岁男性在一家三级护理大学医院的多学科儿科重症监护病房就诊,表现为胸痛、咳嗽和进行性呼吸困难。给予氧气6小时后,血气分析结果为:pH 7.16,二氧化碳分压43托(5.7千帕),动脉血氧分压149托(19.9千帕),碳酸氢盐浓度15毫当量/升。胸部X光片提示肺水肿。第3天,患者称入院前数小时自行注射了Varsol(加拿大帝国石油公司生产)——一种直链和支链碳氢化合物、环烷烃和苯的烷基衍生物的混合物。第5天,患者呼吸频率恢复至20次/分钟,到第7天胸部X光片恢复正常。本病例报告提示,静脉注射碳氢化合物可能导致可逆性肺损伤。

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