Savoia Francesco, Gaddoni Giuseppe, Casadio Chiara, Patrizi Annalisa, Spadola Giuseppe, Bassi Paolo, Albertini Francesco, Ballardini Giuseppe, Briganti Elisabetta, Casolari Stefania, De Donà Davide, Menni Bruno, Zanotti Miriam, De Angelis Paolo
Dermatol Online J. 2010 Feb 15;16(2):13.
Methotrexate may rarely provoke serositis, even with low doses and after just a few weeks of therapy. We report here a rare case of pleuropericarditis due to methotrexate. The effusion resolved after the withdrawal of the drug and the beginning of anti-inflammatory therapy; there was no relapse during a 10-month follow-up.
甲氨蝶呤即便低剂量使用且仅治疗几周，也可能罕见地引发浆膜炎。我们在此报告一例罕见的由甲氨蝶呤引起的胸膜心包炎病例。停药并开始抗炎治疗后，积液消退；在10个月的随访期间未复发。
