一名接受甲氨蝶呤治疗的慢性斑块状银屑病患者发生无菌性胸膜心包炎的病例。
A case of aseptic pleuropericarditis in a patient with chronic plaque psoriasis under methotrexate therapy.
作者信息
Savoia Francesco, Gaddoni Giuseppe, Casadio Chiara, Patrizi Annalisa, Spadola Giuseppe, Bassi Paolo, Albertini Francesco, Ballardini Giuseppe, Briganti Elisabetta, Casolari Stefania, De Donà Davide, Menni Bruno, Zanotti Miriam, De Angelis Paolo
出版信息
Dermatol Online J. 2010 Feb 15;16(2):13.
PMID:20178709
Abstract
Methotrexate may rarely provoke serositis, even with low doses and after just a few weeks of therapy. We report here a rare case of pleuropericarditis due to methotrexate. The effusion resolved after the withdrawal of the drug and the beginning of anti-inflammatory therapy; there was no relapse during a 10-month follow-up.
摘要
甲氨蝶呤即便低剂量使用且仅治疗几周，也可能罕见地引发浆膜炎。我们在此报告一例罕见的由甲氨蝶呤引起的胸膜心包炎病例。停药并开始抗炎治疗后，积液消退；在10个月的随访期间未复发。
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