Palungwachira P, Palungwachira P, Laohathai P
Family Medicine Department, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 1998 Feb;81(2):141-5.
We describe a 62-year-old woman with Psoriasis who presented as Methotrexate-induced pericarditis and pericardial effusion. Aspiration of the pericardium was required and the patient made a satisfactory recovery. At six-months follow-up, she remained well, psoriasis plaques was controlled by topical crude coal tar and topical corticosteroid. These complications are extremely rare, but have been described as isolated phenomena associated with methotrexate therapy.
我们描述了一名62岁的银屑病女性患者，她出现了甲氨蝶呤诱发的心包炎和心包积液。需要进行心包穿刺抽吸，患者恢复良好。在六个月的随访中，她情况良好，银屑病斑块通过外用粗煤焦油和外用皮质类固醇得到控制。这些并发症极为罕见，但已被描述为与甲氨蝶呤治疗相关的孤立现象。
