Department of Ophthalmology, SUNY Downstate Medical Center, Brooklyn, MD, USA.
J Glaucoma. 2010 Oct-Nov;19(8):504-8. doi: 10.1097/IJG.0b013e3181ca7850.
Forty years ago, Molteno introduced the prototype of the present day long tube implant. Since then, modifications in size and shape and introduction of valve system have taken place. Aqueous has been shown to contain proinflammatory substances that have been shown to influence the thickness of the bleb wall, and the hypertensive phase has been seen with the implants. The effect of the aqueous may be modified by the use of systemic antiinflammatory medication or by surgical modification, namely supra-Tenon insertion of the implant. Recent studies have shown that tube implantation is as efficacious as trabeculectomy in patients who were either pseudophakic or earlier had failed filters. Newer nontube implants, such as the Express shunt, have been introduced along with others, such as the gold micro shunt implant and the iStent, presently in clinical trials.
四十年前，Molteno 引入了现今长管植入物的原型。从那时起，大小和形状的改变以及阀门系统的引入已经发生。已经表明房水中含有促炎物质，这些物质会影响泡壁的厚度，并且在植入物中会出现高血压期。通过使用全身抗炎药物或通过手术修改，即植入物上方 Tenon 插入，可改变房水的作用。最近的研究表明，在那些已经白内障或先前滤过失败的患者中，管植入与小梁切除术一样有效。新的非管植入物，如 Express 分流器，已经与其他植入物一起引入，如金微管植入物和 iStent，目前正在临床试验中。
