Laboratory of Dr. W. M. Usrey, Center for Neuroscience, Division of Biological Sciences, University of California Davis, CA, USA.
Front Neural Circuits. 2010 Feb 12;4:3. doi: 10.3389/neuro.04.003.2010. eCollection 2010.
Neurons in the deepest layer of mammalian cerebral cortex are morphologically and physiological diverse and are situated in a strategic position to modulate neuronal activity locally and in other structures. The variety of neuronal circuits within which layer 6 neurons participate differs across species and cortical regions. However even amidst this diversity, common organizational features emerge. Examination of the anatomical and physiological characteristics of different classes of layer 6 neuron, each specialized to participate in distinct circuits, provides insight into the functional contributions of layer 6 neurons toward cortical information processing.
哺乳动物大脑皮层最深处的神经元在形态和生理上具有多样性，并且位于局部和其他结构中调节神经元活动的战略位置。层 6 神经元参与的神经元回路的种类在不同物种和皮质区域之间有所不同。然而，即使在这种多样性中，也出现了共同的组织特征。对不同类型的层 6 神经元的解剖和生理特征的研究，这些神经元各自专门参与不同的回路，深入了解了层 6 神经元对皮质信息处理的功能贡献。
