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心境障碍对美沙酮维持治疗的妊娠患者分娩及新生儿结局的影响。

The impact of mood disorders on the delivery and neonatal outcomes of methadone-maintained pregnant patients.

机构信息

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

Am J Drug Alcohol Abuse. 2009;35(5):358-63. doi: 10.1080/00952990903108231.

DOI:10.1080/00952990903108231
PMID:20180664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3057901/
Abstract

Methadone-maintained pregnant patients with mood disorders have compromised treatment outcomes ( [1] ). This study examined the relationship between the presence of mood disorders and delivery and neonatal outcomes. Participants were categorized into two groups: no current mood disorder (n = 30) or primary mood disorder (n = 38). The mood disorder group reported more serious lifetime and current depression than did the no current mood disorder group. Neonates from mothers with mood disorders had a longer length of stay in the neonatal intensive care unit than the no current mood disorder group. Findings emphasize the need to treat mood disorders in methadone-maintained pregnant patients.

摘要

美沙酮维持治疗的伴发心境障碍的孕妇治疗结局较差(1)。本研究旨在探讨心境障碍与分娩及新生儿结局之间的关系。研究参与者分为两组:无当前心境障碍(n=30)或主要心境障碍(n=38)。心境障碍组的终生和当前抑郁严重程度评分均高于无当前心境障碍组。心境障碍组的新生儿在新生儿重症监护病房的住院时间长于无当前心境障碍组。这些发现强调了对美沙酮维持治疗的孕妇进行心境障碍治疗的必要性。

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本文引用的文献

1
Managing unipolar depression in pregnancy.孕期单相抑郁症的管理
Curr Opin Psychiatry. 2009 Jan;22(1):13-8. doi: 10.1097/YCO.0b013e3283169375.
2
Methadone maintenance vs. methadone taper during pregnancy: maternal and neonatal outcomes.孕期美沙酮维持治疗与美沙酮减量:母婴结局
Am J Addict. 2008 Sep-Oct;17(5):372-86. doi: 10.1080/10550490802266276.
3
Prenatal depression restricts fetal growth.产前抑郁会限制胎儿生长。
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Chronic prenatal depression and neonatal outcome.慢性产前抑郁与新生儿结局。
Int J Neurosci. 2008 Jan;118(1):95-103. doi: 10.1080/00207450601042144.
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Treatment of perinatal mood and anxiety disorders: a review.围产期情绪与焦虑障碍的治疗:综述
Can J Psychiatry. 2007 Aug;52(8):489-98. doi: 10.1177/070674370705200803.
6
Sleep disturbances in depressed pregnant women and their newborns.抑郁孕妇及其新生儿的睡眠障碍。
Infant Behav Dev. 2007 Feb;30(1):127-33. doi: 10.1016/j.infbeh.2006.08.002. Epub 2006 Sep 11.
7
Mood disorders affect drug treatment success of drug-dependent pregnant women.情绪障碍会影响药物依赖孕妇的药物治疗成功率。
J Subst Abuse Treat. 2007 Jan;32(1):19-25. doi: 10.1016/j.jsat.2006.06.015. Epub 2006 Oct 13.
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The maternal lifestyle study: cognitive, motor, and behavioral outcomes of cocaine-exposed and opiate-exposed infants through three years of age.母亲生活方式研究:可卡因暴露和阿片类药物暴露婴儿至三岁时的认知、运动和行为结果。
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Substance use during pregnancy: time for policy to catch up with research.孕期物质使用:政策跟上研究步伐的时候了。
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Prepartum, postpartum, and chronic depression effects on newborns.产前、产后及慢性抑郁症对新生儿的影响。
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