Phillips Edward M, Katula Jeffrey, Miller Michael E, Walkup Michael P, Brach Jennifer S, King Abby C, Rejeski W Jack, Church Tim, Fielding Roger A
Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Tufts University, Boston, MA, USA.
J Aging Phys Act. 2010 Jan;18(1):61-74. doi: 10.1123/japa.18.1.61.
To examine baseline characteristics and change in gait speed and Short Physical Performance Battery (SPPB) scores in participants medically suspended (MS) from a physical activity intervention (PA).
Randomized controlled trial.
University and community centers.
Sedentary older adults (N = 213) randomized to PA in the Lifestyle Interventions and Independence for Elders Pilot (LIFE-P).
MS was defined as missing 3 consecutive PA sessions in adoption and transition phases or 2 wk in maintenance phase because of a health event.
In all, 122 participants completed PA without MS (NMS subgroup), 48 participants underwent MS and resumed PA (SR subgroup), and 43 participants underwent MS and did not complete PA (SNR subgroup). At baseline, SNR walked slower (p = .03), took more prescribed medications (p = .02), and had lower SPPB scores than NMS and SR (p = .02). Changes from baseline to Month 12 SPPB scores were affected by suspension status, adjusted mean (SE) SPPB change: SNR 0.0957 (0.3184), SR 0.9413 (0.3063), NMS 1.0720 (0.1871); p = .03.
MS participants unable to return to complete the PA in a trial of mobility-limited sedentary older adults had slower walking speeds, lower SPPB scores, and a higher number of prescribed medications at baseline. Change in SPPB scores at 12 months was related to suspension status.
研究因健康原因暂停体育活动干预（PA）的参与者的基线特征、步速变化以及简短体能状况量表（SPPB）评分情况。
随机对照试验。
大学和社区中心。
久坐不动的老年人（N = 213），随机分配至老年人生活方式干预与独立性试点研究（LIFE - P）中的体育活动组。
体育活动暂停（MS）定义为在采用和过渡阶段连续错过3次体育活动课程，或在维持阶段因健康事件错过2周的体育活动课程。
总计122名参与者未经历体育活动暂停完成了体育活动（非MS亚组），48名参与者经历了体育活动暂停并恢复了体育活动（SR亚组），43名参与者经历了体育活动暂停且未完成体育活动（SNR亚组）。在基线时，SNR亚组的步速较慢（p = 0.03），服用的处方药更多（p = 0.02），且SPPB评分低于非MS亚组和SR亚组（p = 0.02）。从基线到第12个月SPPB评分的变化受暂停状态影响，调整后的平均（SE）SPPB变化：SNR亚组为0.0957（0.3184），SR亚组为0.9413（0.3063），非MS亚组为1.0720（0.1871）；p = 0.03。
在一项针对行动受限的久坐老年人的试验中，无法恢复完成体育活动的体育活动暂停参与者在基线时步速较慢、SPPB评分较低且服用的处方药数量较多。12个月时SPPB评分的变化与暂停状态有关。
