输血对前列腺癌放射治疗后生存率的影响。
Effect of blood transfusion on survival after radiotherapy as treatment for carcinoma of the prostate.
作者信息
Davies A H, Ramarakha P, Cranston D, Clarke P J
机构信息
Department of Urology, Churchill Hospital, Oxford.
出版信息
Ann R Coll Surg Engl. 1991 Mar;73(2):116-8.
Over a 14-year period, 71 patients underwent transurethral resection of the prostate with high dose radiotherapy. Eighteen patients required perioperative transfusion. The 5-year survival in the non-transfused group was 66% and in the transfused group 17% (P less than 0.001; chi 2 = 11.57). Recurrence of tumour in the transfused group was 72% compared with 21% in the non-transfused group (P less than 0.01; chi 2 = 9.1). When Cox's models and regression analysis were used, the disease state being controlled for grade and stage, only blood transfusion was seen to influence outcome. We conclude that careful thought should be given before transfusing patients undergoing transurethral surgery for prostatic carcinoma.
在14年期间，71例患者接受了高剂量放疗的经尿道前列腺切除术。18例患者需要围手术期输血。未输血组的5年生存率为66%，输血组为17%（P<0.001；卡方=11.57）。输血组肿瘤复发率为72%，未输血组为21%（P<0.01；卡方=9.1）。当使用Cox模型和回归分析时，在控制疾病分级和分期的情况下，仅发现输血会影响预后。我们得出结论，对于接受经尿道前列腺癌手术的患者，在输血前应慎重考虑。
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