Campbell Zachariah, Zakzanis Konstantine K, Jovanovski Diana, Joordens Steve, Mraz Richard, Graham Simon J
Department of Psychology, University of Toronto Scarborough, Toronto, Canada.
Appl Neuropsychol. 2009 Oct;16(4):295-306. doi: 10.1080/09084280903297891.
Virtual reality (VR) was used to create an ecologically valid spatial-navigation task in hand with functional magnetic resonance imaging (fMRI) to articulate the neural basis of planning behavior. A virtual version of a traditional planning measure, the Tower of London, was also developed to ascertain convergent and divergent validity in terms of planning behavior and functional neuroanatomy. This VR-fMRI case study experiment was performed at 3.0 Tesla on a young healthy male subject. The obtained image data suggest both convergent and divergent specificity between the two conditions in terms of location and overall intensity of activation. Overall, the present case study provides supportive evidence that the activity of various brain regions associated with planning tasks is largely modulated by the ecological validity of the measure being used. This finding may extend to all domains of inquiry in neuropsychological research and assessment when deductive conclusions are formulated on the results of neuropsychological test measures that could be considered contrived in nature.
虚拟现实（VR）与功能磁共振成像（fMRI）相结合，用于创建一个生态效度良好的空间导航任务，以阐明计划行为的神经基础。还开发了传统计划测量工具“伦敦塔”的虚拟版本，以确定在计划行为和功能神经解剖学方面的聚合效度和区分效度。这个VR - fMRI案例研究实验是在3.0特斯拉的磁场强度下对一名年轻健康男性受试者进行的。获得的图像数据表明，在激活的位置和整体强度方面，两种条件之间存在聚合特异性和区分特异性。总体而言，本案例研究提供了支持性证据，即与计划任务相关的各个脑区的活动在很大程度上受到所使用测量方法的生态效度的调节。当根据本质上可能被认为是人为设计的神经心理测试测量结果得出演绎结论时，这一发现可能会扩展到神经心理学研究和评估的所有探究领域。
