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变压器和配电线路站工人的遗传毒性风险的生物监测研究。

A biomonitoring study of genotoxic risk to workers of transformers and distribution line stations.

机构信息

Uludag University, Bursa, Turkey.

出版信息

Int J Environ Health Res. 2009 Dec;19(6):421-30. doi: 10.1080/09603120903079356.

DOI:10.1080/09603120903079356
PMID:20183199
Abstract

A cytogenetic monitoring study was carried out on a group of workers from transformer and distribution line stations in the Bursa province of Turkey, to investigate the genotoxic risk of occupational exposure to extremely low frequency electric (ELF) and magnetic fields (EMF). Cytogenetic analysis, namely chromosomal aberrations (CAs) and micronucleus (MN) tests were performed on a strictly selected group of 55 workers and compared to 17 controls. CA and MN frequencies in electrical workers appeared significantly higher than in controls (p < 0.001, 0.05, respectively). The frequency of CA in exposed groups were significantly enhanced with the years of exposure (p < 0.01). The effect of smoking on the level of CA and MN was not significant in the control and exposure groups. The results of this study demonstrated that a significant induction of cytogenetic damage in peripheral lymphocytes of workers engaged to occupational exposure to ELMF in electric transformer and distribution stations.

摘要

本研究旨在探讨职业接触极低频电磁场(ELF-EMF)对工人遗传毒性的风险,对土耳其布尔萨省的一组来自变压器和配电线路站的工人进行了细胞遗传学监测。对严格筛选的 55 名工人和 17 名对照进行了细胞遗传学分析,即染色体畸变(CA)和微核(MN)试验。与对照组相比,电力工人的 CA 和 MN 频率明显更高(分别为 p < 0.001 和 0.05)。暴露组的 CA 频率随暴露年限的增加而显著增强(p < 0.01)。在对照组和暴露组中,吸烟对 CA 和 MN 水平的影响不显著。本研究结果表明,从事电力变压器和配电站职业接触 ELF-MF 的工人外周血淋巴细胞的遗传毒性损伤明显增加。

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