Birchall M A, Stafford N D, Walsh-Waring G P
Ear, Nose and Throat Department, St Mary's Hospital, London.
Ann R Coll Surg Engl. 1991 Mar;73(2):91-5.
The options currently available for establishing the histological diagnosis of a neck mass are open biopsy or a measured approach involving head and neck examination, fine-needle aspiration biopsy (FNAB) and panendoscopy. We present the results of 10 patients initially managed by open biopsy and 22 who were subject to the alternative approach. All had a histological diagnosis of squamous carcinoma. Seven of the open biopsy patients developed problems related to the biopsy that later adversely affected their management. There were no such problems in the other group. Patients undergoing open biopsy required a mean of one further general anaesthetic and a mean inpatient stay of 7 days longer than the patients in the second group. FNAB in our hospital was shown to be reliable (91% accurate, 93% sensitive, 97% specific), especially for squamous malignancy (100% specific). The relative merits of the two methods are discussed. It is our belief that open biopsy should not be used as a first-line investigation of a neck mass.
目前用于确立颈部肿块组织学诊断的方法有开放性活检,或者是一种包括头颈检查、细针穿刺活检(FNAB)和全腔镜检查在内的有步骤的方法。我们给出了10例最初采用开放性活检治疗患者以及22例采用另一种方法治疗患者的结果。所有患者的组织学诊断均为鳞状细胞癌。7例开放性活检患者出现了与活检相关的问题,这些问题后来对其治疗产生了不利影响。另一组则没有此类问题。接受开放性活检的患者平均还需要再进行一次全身麻醉,住院时间比第二组患者平均长七天。我院的细针穿刺活检显示是可靠的(准确率91%,敏感度93%,特异度97%),尤其是对于鳞状恶性肿瘤(特异度100%)。讨论了两种方法的相对优点。我们认为开放性活检不应作为颈部肿块的一线检查方法。