来自中国南海海绵Axinella sp.的类固醇和生物碱

Steroids and alkaloids from the South China Sea sponge Axinella sp.

作者信息

Qi Shu-Hua, Wang Yi-Fei, Zhang Si

机构信息

Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, Guangzhou, China.

出版信息

J Asian Nat Prod Res. 2009 Dec;11(12):1040-4. doi: 10.1080/10286020903367136.

DOI:10.1080/10286020903367136

PMID:20183274

Abstract

A new steroid 24beta-methylcholasta-1,8,14,22,25-penten-3-one-5alpha-ol (1) and a new alkaloid 1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane (2), together with four known compounds, were isolated from the EtOH extract of the South China Sea sponge Axinella sp. The structures of 1 and 2 were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR spectral data.

摘要

从中国南海海绵Axinella sp.的乙醇提取物中分离出一种新的甾体24β-甲基胆甾-1,8,14,22,25-戊烯-3-酮-5α-醇（1）和一种新的生物碱1-(1H-吲哚-3-基)-2,3-二羟基-5-甲基己烷（2），以及四种已知化合物。通过广泛的光谱分析，包括一维和二维核磁共振光谱数据，确定了1和2的结构。