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鸦胆子种子中具有烟草花叶病毒抑制活性的成分。

Constituents from the seeds of Brucea javanica with inhibitory activity of Tobacco mosaic virus.

作者信息

Chen Qi-Jian, Ouyang Ming-An, Tan Qing-Wei, Zhang Zheng-Kun, Wu Zu-Jian, Lin Qi-Ying

机构信息

Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.

出版信息

J Asian Nat Prod Res. 2009 Jun;11(6):539-47. doi: 10.1080/10286020902932708.

DOI:10.1080/10286020902932708
PMID:20183288
Abstract

Three new constituents were obtained along with 10 known compounds from the seeds of Brucea javanica. The structures of these compounds were determined based on spectral and chemical evidence. These new compounds included a monoterpenoid glycoside and two sesquiterpenes. Bioactivity screening of these constituents showed that compounds 1, 3, 8, 9, and 13 with obvious activities in inhibiting multiplication of the Tobacco mosaic virus.

摘要

从鸦胆子的种子中除得到10个已知化合物外,还获得了3个新成分。这些化合物的结构通过光谱和化学证据得以确定。这些新化合物包括一个单萜糖苷和两个倍半萜。对这些成分的生物活性筛选表明,化合物1、3、8、9和13在抑制烟草花叶病毒增殖方面具有明显活性。

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