两种来自小蓟的新萜类糖苷及抗肿瘤剂。

Two new terpene glucosides and antitumor agents from Centipeda minima.

作者信息

Ding Lin-Fen, Liu Ying, Liang Heng-Xing, Liu Da-Peng, Zhou Guang-Biao, Cheng Yong-Xian

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.

出版信息

J Asian Nat Prod Res. 2009 Aug;11(8):732-6. doi: 10.1080/10286020903029231.

DOI:10.1080/10286020903029231

PMID:20183316

Abstract

One new monoterpene glucoside minimaoside A (1) and one new sesquiterpene glucoside minimaoside B (2), together with four known terpenoids, were isolated from the whole plants of Centipeda minima (L.) A. Braun et Ashers. Their structures were determined by spectroscopic methods. Compounds 5 and 6 showed weak or moderate cytotoxic activity toward several tumor cell lines.

摘要

从最小马兰（Centipeda minima (L.) A. Braun et Ashers）的全草中分离出一个新的单萜糖苷最小苷A（1）和一个新的倍半萜糖苷最小苷B（2），以及四种已知的萜类化合物。通过光谱方法确定了它们的结构。化合物5和6对几种肿瘤细胞系显示出弱或中等的细胞毒活性。