A novel norditerpenoid alkaloid from Aconitum macrorhynchum.

作者信息

Yang Li-Juan, Luo Yi-Ping, Chen Wen, Zhao Jing-Feng, Yang Xiao-Dong, Li Liang

机构信息

Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, China.

出版信息

J Asian Nat Prod Res. 2009 Aug;11(8):728-31. doi: 10.1080/10286020903029223.

DOI:10.1080/10286020903029223

PMID:20183315

Abstract

A novel norditerpenoid alkaloid, macrorhynine C (1), together with three known compounds, was isolated from Aconitum macrorhynchum. The structure of the new alkaloid was elucidated on the basis of spectral analyses as (1alpha,6alpha,16beta)-3-hydroxy-8-acetyloxy-13-hydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-19-ene-aconitan-14-yl 4-methoxybenzoate (1). The novel compound was found to contain the rare C(19) = N azomethine group. Compounds 2-4 were obtained from this species for the first time.

摘要