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正常发育儿童与糖尿病母亲所生儿童情绪加工的神经关联。

Neural correlates of emotion processing in typically developing children and children of diabetic mothers.

作者信息

Cordón Ingrid M, Georgieff Michael K, Nelson Charles A

机构信息

Center for Public Policy Research, University of California-Davis, Davis, California, USA.

出版信息

Dev Neuropsychol. 2009;34(6):683-700. doi: 10.1080/87565640903265129.

Abstract

To examine the neurocognitive sequelae of children born to diabetic mothers (CDMs), event-related potentials (ERPs) in response to three facial expressions (happy, fear, anger) were collected from 42 children (18 CDMs, 24 controls), aged 36 and/or 48 months. A linear mixed models approach was used to model individual variation in amplitude and latency. As infants, CDMs in the present study displayed subtle impairments in attention and memory processing, including face recognition, as indexed by ERPs. Findings indicate that these same children, now ages 3-4 years, continue to display ERP patterns that differ from controls in amplitude, latency, and hemispheric asymmetry.

摘要

为研究糖尿病母亲所生儿童(CDM)的神经认知后遗症,从42名36个月和/或48个月大的儿童(18名CDM,24名对照)中收集了对三种面部表情(快乐、恐惧、愤怒)做出反应的事件相关电位(ERP)。采用线性混合模型方法对振幅和潜伏期的个体差异进行建模。作为婴儿,本研究中的CDM在注意力和记忆处理方面表现出细微的损伤,包括通过ERP指标衡量的面部识别。研究结果表明,这些现在3至4岁的儿童在振幅、潜伏期和半球不对称性方面的ERP模式仍与对照组不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5665/2935698/2be1a264bb71/nihms153107f1.jpg

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