Lindahl B, Gullberg B
Department of Obstetrics and Gynecology, Lund University, Sweden.
Anticancer Res. 1991 Jan-Feb;11(1):397-401.
In almost all studies regarding flow cytometry and endometrial carcinoma, the DNA factors used are stronger prognostic parameters than the clinical factors previously used. Number of sub-populations and/or percentage of cells in S-phase are mostly used to select those tumors with the worst prognosis. In this study, reporting the 2 year follow-up of 245 patients (222 followed for more than 2 years), we claim that the DNA-index is a stronger prognostic tool than other DNA parameters, but also that the range of myometrial invasion is a stronger predictor than all other parameters including the DNA. Range of myometrial invasion and DNA index are used to form one high-risk group, consisting of 22% of the patients with a relapse rate of 38%, and one low-risk group, consisting of 47% of the patients with a relapse rate of 4%.
在几乎所有关于流式细胞术和子宫内膜癌的研究中，所使用的DNA因素比先前使用的临床因素是更强的预后参数。S期亚群数量和/或细胞百分比大多用于选择预后最差的那些肿瘤。在本研究中，报告了245例患者的2年随访情况（222例随访超过2年），我们声称DNA指数是比其他DNA参数更强的预后工具，而且肌层浸润范围比包括DNA在内的所有其他参数是更强的预测指标。肌层浸润范围和DNA指数用于形成一个高危组，由22%的患者组成，复发率为38%，以及一个低危组，由47%的患者组成，复发率为4%。
