Section of Dermatology, Department of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, SE-118 83 Stockholm, Sweden.
Br J Dermatol. 2010 Jun;162(6):1261-8. doi: 10.1111/j.1365-2133.2010.09715.x. Epub 2010 Feb 22.
Hidradenitis suppurativa (HS) is a chronic recurrent disease with scars and sinus tract formation that causes substantial impact on quality of life. For evaluation of HS and treatment results, a scoring system for disease severity (Hidradenitis Suppurativa Score, HSS) has been proposed.
To describe the interobserver reliability of the HSS and further to document its correlation with risk factors and other measures of disease severity.
Sixty-one consecutive patients with HS, referred to a clinical centre with special interest in the disease, were scored according to the HSS protocol: eight patients by four dermatologists together, 23 patients by all four observers independently and 30 patients by a single observer. Interobserver variability in HSS between the four observers was investigated in the group of 23 patients. Patients' reports of weight and height, smoking habits etc., were collected, as well as Dermatology Life Quality Index (DLQI) questionnaires.
The interobserver concordance of HSS was 0·95. Median (interquartile range, IQR) HSS for all patients was 40 (18-73); women 39 (16-68); men 60·5 (30-95). Median (IQR) HSS for nonsmokers was 26 (12-65); former smokers 30 (10-56); smokers 44 (26-108). Median (IQR) HSS for normal weight patients was 12 (10-30); overweight 43 (25-58); obese 51 (24-95). Mean ± SD DLQI for all patients was 11·3 ± 8·6.
HSS is simple to use and shows low interobserver variability. The score correlates with suggested risk factors, indicating that it reflects a valid estimation of disease severity.
化脓性汗腺炎（HS）是一种慢性复发性疾病，可导致瘢痕和窦道形成，对生活质量造成重大影响。为了评估 HS 疾病严重程度和治疗效果，已经提出了一种疾病严重程度评分系统（Hidradenitis Suppurativa Score，HSS）。
描述 HSS 的观察者间可靠性，并进一步记录其与危险因素和其他疾病严重程度指标的相关性。
61 例连续的 HS 患者，来自对该疾病有特殊兴趣的临床中心，根据 HSS 方案进行评分：4 位皮肤科医生对 8 例患者共同评分，4 位观察者对 23 例患者独立评分，1 位观察者对 30 例患者评分。在 23 例患者中研究了 4 位观察者之间 HSS 的观察者间变异性。收集了患者的体重和身高、吸烟习惯等报告，以及皮肤病生活质量指数（Dermatology Life Quality Index，DLQI）问卷。
HSS 的观察者间一致性为 0.95。所有患者的 HSS 中位数（四分位距，IQR）为 40（18-73）；女性 39（16-68）；男性 60.5（30-95）。不吸烟者的 HSS 中位数（IQR）为 26（12-65）；前吸烟者 30（10-56）；吸烟者 44（26-108）。体重正常患者的 HSS 中位数（IQR）为 12（10-30）；超重者为 43（25-58）；肥胖者为 51（24-95）。所有患者的平均 ± SD DLQI 为 11.3±8.6。
HSS 使用简单，观察者间变异性低。该评分与提示的危险因素相关，表明它反映了对疾病严重程度的有效评估。
