302例法国化脓性汗腺炎患者的临床特征，以及与疾病严重程度相关因素的分析。

Clinical characteristics of a series of 302 French patients with hidradenitis suppurativa, with an analysis of factors associated with disease severity.

作者信息

Canoui-Poitrine Florence, Revuz Jean E, Wolkenstein Pierre, Viallette Cédric, Gabison Germaine, Pouget Florence, Poli Florence, Faye Ousmane, Bastuji-Garin Sylvie

机构信息

Laboratoire d'Investigation Clinique EA4393, Université Paris 12, Créteil, France.

出版信息

J Am Acad Dermatol. 2009 Jul;61(1):51-7. doi: 10.1016/j.jaad.2009.02.013. Epub 2009 Apr 29.

DOI:10.1016/j.jaad.2009.02.013

PMID:19406505

Abstract

BACKGROUND

Factors associated with the severity of hidradenitis suppurativa (HS) are not known.

OBJECTIVE

We sought to identify factors associated with the severity of HS.

METHODOLOGY

The severity of disease in a series of 302 consecutive patients with HS was assessed using the Sartorius score.

RESULTS

Atypical locations were more common in men than in women (47.1% vs 14.8%; P < .001). Men also had more severe disease (median Sartorius score: 20.5 vs 16.5; P = .02). Increased body mass index (P < .001), atypical locations (P = .002), a personal history of severe acne (P = .04), and absence of a family history of HS (P = .06) were associated with an increased Sartorius score. The Sartorius score was highly correlated with the intensity and duration of pain and suppuration (all P values < .001).

LIMITATIONS

The referral center base of the study may have biased recruitment.

CONCLUSION

Our data showed a significant association between the severity of HS and several clinical and behavioral factors. Prospective studies are needed to confirm the prognostic role of these factors.

摘要

背景

化脓性汗腺炎（HS）严重程度相关因素尚不清楚。

目的

我们试图确定与HS严重程度相关的因素。

方法

使用萨托里厄斯评分对连续302例HS患者的疾病严重程度进行评估。

结果

非典型部位在男性中比女性更常见（47.1%对14.8%；P < 0.001）。男性的疾病也更严重（萨托里厄斯评分中位数：20.5对16.5；P = 0.02）。体重指数增加（P < 0.001）、非典型部位（P = 0.002）、重度痤疮个人史（P = 0.04）以及无HS家族史（P = 0.06）与萨托里厄斯评分增加相关。萨托里厄斯评分与疼痛和化脓的强度及持续时间高度相关（所有P值 < 0.001）。