• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

分开抚养的同卵双胞胎的体脂:基因与环境的作用。

Body fat in identical twins reared apart: roles for genes and environment.

作者信息

Price R A, Gottesman I I

机构信息

Department of Psychiatry, University of Pennsylvania, Philadelphia 19104-4283.

出版信息

Behav Genet. 1991 Jan;21(1):1-7. doi: 10.1007/BF01067662.

DOI:10.1007/BF01067662
PMID:2018460
Abstract

We report analyses of data on body fat from a cohort of 34 separated monozygotic twin pairs (MZA) and a matched sample of 38 pairs of monozygotic twins reared together (MZT) originally studied by James Shields. The correlation for MZA pairs was .61 and the correlation for MZT pairs was .75. These correlations did not differ significantly, nor did correlations differ between MZA pairs subclassified as having been raised in relatively more or less similar environments. Our results suggest important roles for both genes and environment in the accumulation of body fat and support other adoption studies in suggesting that adult environments rather than rearing environments are the most important nongenetic determinants of levels of body fat in adults.

摘要

我们报告了对一组34对分开抚养的同卵双胞胎(MZA)以及38对一起抚养的同卵双胞胎(MZT)匹配样本的身体脂肪数据的分析,这些样本最初由詹姆斯·希尔兹进行研究。MZA双胞胎对的相关性为0.61,MZT双胞胎对的相关性为0.75。这些相关性没有显著差异,在分类为在相对更相似或更不相似环境中长大的MZA双胞胎对之间,相关性也没有差异。我们的结果表明,基因和环境在身体脂肪积累中都起着重要作用,并支持其他收养研究,表明成人环境而非成长环境是成年人身体脂肪水平最重要的非遗传决定因素。

相似文献

1
Body fat in identical twins reared apart: roles for genes and environment.分开抚养的同卵双胞胎的体脂:基因与环境的作用。
Behav Genet. 1991 Jan;21(1):1-7. doi: 10.1007/BF01067662.
2
Heritability of MMPI personality indicators of psychopathology in twins reared apart.分开抚养的双胞胎中精神病理学的明尼苏达多相人格量表人格指标的遗传力。
J Abnorm Psychol. 1996 Nov;105(4):491-9. doi: 10.1037//0021-843x.105.4.491.
3
Serum lipids and apolipoprotein E phenotypes in identical twins reared apart.
Clin Genet. 1998 Mar;53(3):191-9. doi: 10.1111/j.1399-0004.1998.tb02675.x.
4
The mechanism of emergenesis.突现发生的机制。
Genes Brain Behav. 2006 Jun;5(4):306-10. doi: 10.1111/j.1601-183X.2006.00233.x.
5
Importance of genetic effects for monoamine oxidase activity in thrombocytes in twins reared apart and twins reared together.遗传效应在分开抚养的双胞胎和共同抚养的双胞胎血小板中单胺氧化酶活性中的重要性。
Psychiatry Res. 1993 Mar;46(3):239-51. doi: 10.1016/0165-1781(93)90092-u.
6
The heritability of body mass index among an international sample of monozygotic twins reared apart.在国际样本中,分开抚养的同卵双胞胎的体重指数遗传度。
Int J Obes Relat Metab Disord. 1996 Jun;20(6):501-6.
7
Common genetic components of obesity traits and serum leptin.肥胖特征与血清瘦素的常见遗传成分。
Obesity (Silver Spring). 2008 Dec;16(12):2723-9. doi: 10.1038/oby.2008.440. Epub 2008 Oct 16.
8
Resemblance for age at menarche in female twins reared apart and together.分开抚养和共同抚养的女性双胞胎初潮年龄的相似性。
Hum Biol. 2007 Dec;79(6):623-35. doi: 10.1353/hub.2008.0015.
9
Helicobacter pylori infection: genetic and environmental influences. A study of twins.幽门螺杆菌感染:遗传和环境影响。一项双胞胎研究。
Ann Intern Med. 1994 Jun 15;120(12):982-6. doi: 10.7326/0003-4819-120-12-199406150-00002.
10
Shared rearing environment in migraine: results from twins reared apart and twins reared together.偏头痛中的共同养育环境:分开养育与共同养育双胞胎的研究结果
Headache. 2003 Mar;43(3):235-44. doi: 10.1046/j.1526-4610.2003.03047.x.

引用本文的文献

1
A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in Associated With Reduced Energy Expenditure in American Indians.一项使用定制基因分型芯片的全基因组关联研究确定了与美洲印第安人能量消耗降低相关的变异。
Diabetes. 2017 Aug;66(8):2284-2295. doi: 10.2337/db16-1565. Epub 2017 May 5.
2
Mini-review: Obesity in Caribbean Youth.迷你综述:加勒比地区青少年肥胖问题
West Indian Med J. 2015 Jun;64(3):250-62. doi: 10.7727/wimj.2014.379. Epub 2015 Apr 1.
3
Effect of Body Composition Methodology on Heritability Estimation of Body Fatness.

本文引用的文献

1
The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex.遗传背景对小鼠糖尿病位点突变表达的影响。III. H-2单倍型和性别的影响。
Diabetes. 1981 Dec;30(12):1029-34. doi: 10.2337/diab.30.12.1029.
2
An adoption study of human obesity.一项关于人类肥胖的收养研究。
N Engl J Med. 1986 Jan 23;314(4):193-8. doi: 10.1056/NEJM198601233140401.
3
Health implications of obesity: an NIH Consensus Development Conference.肥胖对健康的影响:美国国立卫生研究院共识发展会议
身体成分测量方法对体脂遗传性估计的影响。
Open Nutr J. 2012 Apr 5;6:48-58. doi: 10.2174/1874288201206010048.
4
Mitochondrial DNA variants in obesity.肥胖中的线粒体DNA变异
PLoS One. 2014 May 2;9(5):e94882. doi: 10.1371/journal.pone.0094882. eCollection 2014.
5
Metabolic thrift and the genetic basis of human obesity.代谢节俭与人类肥胖的遗传基础。
Ann Surg. 2014 Apr;259(4):642-8. doi: 10.1097/SLA.0000000000000361.
6
Effect of the β3-adrenergic receptor gene polymorphism Trp64Arg on BMI reduction associated with an exercise-based intervention program in Japanese middle-aged males.β3-肾上腺素能受体基因多态性 Trp64Arg 对日本中年男性运动干预计划相关 BMI 降低的影响。
Environ Health Prev Med. 2010 Nov;15(6):392-7. doi: 10.1007/s12199-010-0157-y. Epub 2010 May 26.
7
Ethnicity, body mass, and genome-wide data.种族、体重和全基因组数据。
Biodemography Soc Biol. 2010;56(2):123-36. doi: 10.1080/19485565.2010.524589.
8
Genetic information, obesity, and labor market outcomes.遗传信息、肥胖与劳动力市场结果。
Health Econ. 2008 Sep;17(9):1089-104. doi: 10.1002/hec.1383.
9
Genetics of obesity.肥胖的遗传学
Philos Trans R Soc Lond B Biol Sci. 2006 Jul 29;361(1471):1095-105. doi: 10.1098/rstb.2006.1850.
10
Possible genomic imprinting of three human obesity-related genetic loci.三个人类肥胖相关基因座可能的基因组印记
Am J Hum Genet. 2005 Mar;76(3):427-37. doi: 10.1086/428438. Epub 2005 Jan 12.
Int J Obes. 1985;9(3):155-70.
4
A twin study of human obesity.一项关于人类肥胖的双胞胎研究。
JAMA. 1986 Jul 4;256(1):51-4.
5
Genetic contributions to human fatness: an adoption study.
Am J Psychiatry. 1987 Aug;144(8):1003-8. doi: 10.1176/ajp.144.8.1003.
6
Sensitivity to overfeeding: the Quebec experiment with identical twins.对过度喂养的敏感性:魁北克同卵双胞胎实验
Prog Food Nutr Sci. 1988;12(1):45-72.
7
Confirming unexpressed genotypes for schizophrenia. Risks in the offspring of Fischer's Danish identical and fraternal discordant twins.确认精神分裂症未表达的基因型。费舍尔丹麦同卵和异卵不一致双胞胎后代的风险。
Arch Gen Psychiatry. 1989 Oct;46(10):867-72. doi: 10.1001/archpsyc.1989.01810100009002.
8
Genetic linkage in schizophrenia: perspectives from genetic epidemiology.
Schizophr Bull. 1989;15(3):453-64. doi: 10.1093/schbul/15.3.453.
9
Commingling analysis of obesity in twins.
Hum Hered. 1989;39(3):121-35. doi: 10.1159/000153848.
10
Genetics of obesity in adult adoptees and their biological siblings.成年领养者及其亲生兄弟姐妹的肥胖遗传学
BMJ. 1989 Jan 14;298(6666):87-90. doi: 10.1136/bmj.298.6666.87.