Terada Tadashi
Department of Pathology, Shizuoka City Shimizu Hospital, Shizuoka, Japan.
Cases J. 2009 Aug 4;2:6661. doi: 10.1186/1757-1626-0002-0000006661.
The author reports two cases of adenosquamous carcinoma arising from endometriosis of ovaries. The tumor patients were 38-year-old and 53-year-old women. Both patients underwent hysterectomy and bilateral salpingo-oophorectomy for ovarian carcinomas. Grossly, both ovarian tumors were located in the left ovaries, and were cystic tumors with mural tumors. Histologically, the cystic areas consisted of endometrial glandular epithelium. Both mural tumors were composed of grade I endometroid adenocarcinoma and squamous cell carcinoma. These two elements were admixed in some areas. A differentiation of endometrioid adenocarcinoma from the endometriosis were present in a few areas. Likewise, a differentiation of squamous cell carcinoma from the endometriosis were recognized in several areas. The pathologic diagnosis was adenosquamous carcinoma arising from endometriosis of the ovary in both cases, rather than endometrioid adenocarcinoma with malignant squamous differentiation. No tumors were present in other organs.
作者报告了两例起源于卵巢子宫内膜异位症的腺鳞癌病例。肿瘤患者为38岁和53岁的女性。两名患者均因卵巢癌接受了子宫切除术和双侧输卵管卵巢切除术。大体上，两个卵巢肿瘤均位于左侧卵巢，为伴有壁内肿瘤的囊性肿瘤。组织学上，囊性区域由子宫内膜腺上皮组成。两个壁内肿瘤均由I级子宫内膜样腺癌和鳞状细胞癌组成。这两种成分在某些区域混合存在。少数区域存在子宫内膜样腺癌与子宫内膜异位症的鉴别。同样，在几个区域也识别出鳞状细胞癌与子宫内膜异位症的鉴别。两例病例的病理诊断均为起源于卵巢子宫内膜异位症的腺鳞癌，而非伴有恶性鳞状分化的子宫内膜样腺癌。其他器官未发现肿瘤。
