Department of Psychiatry and Psychotherapy, Charité University Medicine, Campus Benjamin Franklin, Eschenallee 3, 14050 Berlin, Germany.
Int J Psychophysiol. 2010 May;76(2):72-9. doi: 10.1016/j.ijpsycho.2010.02.005. Epub 2010 Feb 23.
Selective visual attention is thought to be comprised of distinct neuronal networks that serve different attentional functions. The Attention Network Test (ANT) has been introduced to allow for assessment of alerting, orienting, and response inhibition. Information on associated measures of neural processing during ANT is still scarce. We topographically analyzed top-down ANT effects on visual event-related potential morphology in 44 healthy participants. Significant reaction time effects were obtained for all attention networks. Posterior cue-locked target N1 amplitude was significantly increased during both alerting and orienting. P3 amplitude was significantly modulated at frontal and parietal leads as a function of inhibition. Our data suggests that attentional mechanisms of alerting and orienting are employed simultaneously at early stages of the visual processing stream to amplify perceptual discrimination and load onto the same ERP component. Fronto-parietal modulations of P3 amplitude seem to mirror both response inhibition and visual target detection and may be interesting markers for further studies.
选择性视觉注意力被认为由不同的神经元网络组成，这些网络分别具有不同的注意力功能。注意力网络测试（ANT）的引入允许评估警觉、定向和反应抑制。关于 ANT 期间相关神经处理的信息仍然很少。我们对 44 名健康参与者的自上而下的 ANT 对视觉事件相关电位形态的影响进行了地形分析。所有注意力网络都得到了显著的反应时效应。在警觉和定向期间，后线索锁定的目标 N1 振幅明显增加。P3 振幅在前额和顶叶导联上作为抑制的函数显著调节。我们的数据表明，警觉和定向的注意力机制在视觉处理流的早期阶段同时被用来放大感知辨别，并加载到相同的 ERP 成分上。P3 振幅的额顶叶调制似乎反映了反应抑制和视觉目标检测，并且可能是进一步研究的有趣标记。
