Su Hai, Wang Jiwei, Zhu Yanhua, Wang Guangfu, Cheng Xiaoshu
Department of Cardiology, Second Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, PR China.
Blood Press Monit. 2010 Jun;15(3):152-7. doi: 10.1097/MBP.0b013e328337cea6.
To investigate the discrepancy in three blood pressure (BP) readings within one measurement and the relevant influencing factors.
BP was measured by senior experienced physicians three times at 2-min intervals in 2087 adults (1025 male and 1062 female) with a calibrated mercurial sphygmomanometer. According to the history of hypertension and use of antihypertensive drugs, the participants were divided into hypertensive (EH group, 496 cases, 365 on antihypertensive therapy and 131 not on therapy) and normotensive groups (NT group). The average of three BP readings was used as the basic BP. The discrepancy in systolic BP (DeltaSBP) and diastolic BP (DeltaDBP) was the difference between the maximal and the minimal SBP and DBP of three readings respectively. The ratios of DeltaSBP/SBP and DeltaDBP/DBP were calculated from DeltaBP and the basic BP respectively.
The DeltaSBP of more than 10 mmHg occurred in 19.9% of the population and DeltaDBP of more than 5 mmHg in 32.3% of the population. Rank correlation showed a positive relationship between the basic SBP and DeltaSBP (r=0.109, P=0.001), but no relationship was found between basic SBP and DeltaSBP/SBP. Although the SBP and DeltaSBP were higher in the EH group than in the NT group, no significant difference of DeltaSBP/SBP was found between the EH group and the NT group. A positive relationship between age rank and DeltaSBP (r=0.124, P<0.01) and between age rank and DeltaSBP/SBP (r=0.151, P<0.01) existed in the whole population before elderly. Meanwhile, a stronger relationship between age rank and DeltaSBP/SBP was found in females (r=0.163) than in males (r=0.146). Significantly higher DeltaSBP and DeltaSBP/SBP and DeltaDBP and DeltaDBP/DBP were found in females than in males at lower SBP and DBP levels.
The discrepancy in the three BP readings within one measurement is quite large. High basic BP, female sex, and aging are facilitating factors for large SBP discrepancy. Female sex and aging are independent factors for large discrepancy in three BP readings.
探讨一次测量中三次血压读数的差异及相关影响因素。
由经验丰富的资深医生使用校准后的汞柱式血压计,对2087名成年人(男性1025名,女性1062名)每隔2分钟测量一次血压,共测量三次。根据高血压病史及降压药物使用情况,将参与者分为高血压组(EH组,496例,其中365例接受降压治疗,131例未接受治疗)和血压正常组(NT组)。三次血压读数的平均值作为基础血压。收缩压差异(DeltaSBP)和舒张压差异(DeltaDBP)分别为三次读数中最高和最低收缩压及舒张压之间的差值。DeltaSBP/SBP和DeltaDBP/DBP比值分别由DeltaBP和基础血压计算得出。
DeltaSBP超过10 mmHg的情况在19.9%的人群中出现,DeltaDBP超过5 mmHg的情况在32.3%的人群中出现。等级相关分析显示基础收缩压与DeltaSBP呈正相关(r = 0.109,P = 0.001),但基础收缩压与DeltaSBP/SBP之间未发现相关性。虽然EH组的收缩压和DeltaSBP高于NT组,但EH组与NT组之间的DeltaSBP/SBP无显著差异。在老年之前的总体人群中,年龄等级与DeltaSBP呈正相关(r = 0.124,P < 0.01),年龄等级与DeltaSBP/SBP呈正相关(r = 0.151,P < 0.01)。同时,女性(r = 0.163)中年龄等级与DeltaSBP/SBP的关系比男性(r = 0.146)更强。在较低的收缩压和舒张压水平下,女性的DeltaSBP、DeltaSBP/SBP、DeltaDBP和DeltaDBP/DBP显著高于男性。
一次测量中三次血压读数的差异相当大。高基础血压、女性性别和老龄化是收缩压差异较大的促进因素。女性性别和老龄化是三次血压读数差异较大的独立因素。