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加拿大急性哮喘住院患者:一项前瞻性、多中心研究。

Admissions to Canadian hospitals for acute asthma: a prospective, multicentre study.

机构信息

University of Alberta, Edmonton, Alberta, Canada.

出版信息

Can Respir J. 2010 Jan-Feb;17(1):25-30. doi: 10.1155/2010/178549.

Abstract

BACKGROUND

Asthma exacerbations constitute one of the most common causes of emergency department (ED) attendance in most developed countries. While severe asthma often requires hospitalization, variability in admission practices has been observed.

OBJECTIVE

To describe the factors associated with admission to Canadian hospitals for acute asthma after ED treatment.

METHODS

Subjects 18 to 55 years of age treated for acute asthma in 20 Canadian EDs prospectively underwent a structured ED interview (n=695) and telephone interview two weeks later.

RESULTS

The median age of the patients was 30 years, and the majority were women (62.8%). The admission rate was 13.1% (95% CI 10.7% to 15.8%). Admitted patients were older, more often receiving oral or inhaled corticosteroids at presentation, and more frequently receiving systemic corticosteroids and magnesium sulphate in the ED. Similar proportions received beta-2 agonists and/or ipratropium bromide within 1 h of arrival. On multivariable analyses, factors associated with admission included age, previous admission in the past two years, more than eight beta-2 agonist puffs in the past 24 h, a Canadian Triage and Acuity Score of 1 to 2, a respiratory rate of greater than 22 breaths/min and an oxygen saturation of less than 95%.

CONCLUSION

The admission rate for acute asthma from these Canadian EDs was lower than reported in other North American studies. The present study provides insight into practical factors associated with admission for acute asthma and highlights the importance of history and asthma severity markers on ED decision making. Further efforts to standardize ED management and expedite admission decision-making appear warranted.

摘要

背景

在大多数发达国家,哮喘加重是导致急诊科(ED)就诊的最常见原因之一。虽然严重哮喘通常需要住院治疗,但观察到入院实践存在差异。

目的

描述与加拿大 ED 治疗后因急性哮喘入院相关的因素。

方法

在 20 家加拿大 ED 接受急性哮喘治疗的 18 至 55 岁患者前瞻性接受了结构化 ED 访谈(n=695)和两周后的电话访谈。

结果

患者的中位年龄为 30 岁,大多数为女性(62.8%)。入院率为 13.1%(95%CI 10.7%至 15.8%)。入院患者年龄较大,就诊时更常接受口服或吸入皮质类固醇治疗,在 ED 中更常接受全身皮质类固醇和硫酸镁治疗。接受β-2 激动剂和/或异丙托溴铵在到达后 1 小时内的比例相似。多变量分析显示,与入院相关的因素包括年龄、过去两年内的住院史、过去 24 小时内使用超过 8 次β-2 激动剂、加拿大分诊和急症评分 1 至 2、呼吸频率大于 22 次/分钟和血氧饱和度低于 95%。

结论

这些加拿大 ED 治疗的急性哮喘入院率低于其他北美研究报告的入院率。本研究深入了解了与急性哮喘入院相关的实际因素,并强调了 ED 决策中病史和哮喘严重程度标志物的重要性。似乎有必要进一步努力标准化 ED 管理并加快入院决策。

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