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出生后第一年主动脉缩窄手术的早期及长期结果

The early and long-term results of surgery for coarctation of the aorta in the 1st year of life.

作者信息

Shrivastava C P, Monro J L, Shore D F, Lamb R K, Sutherland G R, Fong L V, Keeton B R

机构信息

Wessex Cardiothoracic Centre, Southampton General Hospital, Shirley, UK.

出版信息

Eur J Cardiothorac Surg. 1991;5(2):61-6. doi: 10.1016/1010-7940(91)90002-2.

Abstract

The cases of 110 infants less than 1 year of age, who had surgical repair for coarctation of the aorta between June 1974 and February 1988, were analysed. Three groups of patients were identified. In group 1 there were 39 patients with isolated coarctation. In group 2 there were 25 infants with additional ventricular septal defects (VSD), while in group 3 there were 46 infants with other associated congenital cardiac defects. Repair was performed using the subclavian flap aortoplasty (SFA) procedure in 83 patients, resection with end-to-end anastomosis (EEA) in 23, patch aortoplasty in 3 and Goretex tube bypass in 1. Twenty-eight patients had simultaneous pulmonary artery banding and one concomitant closure of the VSD. The overall early mortality rate was 8.2% (5.1% in group 1, 0% in group 2, and 15.2% in group 3). Age at operation (under 1 month, p = 0.04) and other associated cardiac anomalies (p = 0.03) increased early mortality significantly. There were 11 late deaths (10.8%) among 101 patients followed from 1 to 15 years (mean 5.3 years). Twelve patients underwent further surgery for recoarctation, eight of them within 11 months. A further 11 patients currently have a Doppler gradient across their coarctation site of more than 20 mmHg, but have not undergone further surgery to the coarctation repair site.

摘要

对1974年6月至1988年2月期间接受主动脉缩窄手术修复的110例1岁以下婴儿病例进行了分析。确定了三组患者。第1组有39例单纯主动脉缩窄患者。第2组有25例婴儿伴有室间隔缺损(VSD),而第3组有46例婴儿伴有其他相关先天性心脏缺陷。83例患者采用锁骨下皮瓣主动脉成形术(SFA)进行修复,23例采用端端吻合术(EEA)切除,3例采用补片主动脉成形术,1例采用戈尔特斯管搭桥术。28例患者同时进行了肺动脉环扎术,1例同时闭合了室间隔缺损。总体早期死亡率为8.2%(第1组为5.1%,第2组为0%,第3组为15.2%)。手术年龄(1个月以下,p = 0.04)和其他相关心脏异常(p = 0.03)显著增加早期死亡率。在101例随访1至15年(平均5.3年)的患者中有11例晚期死亡(10.8%)。12例患者因再狭窄接受了进一步手术,其中8例在11个月内。另有11例患者目前在其缩窄部位的多普勒压差超过20 mmHg,但尚未对缩窄修复部位进行进一步手术。

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