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出生后前三个月主动脉缩窄的修复:近期及长期结果

Repair of aortic coarctation in the first three months of life: immediate and long-term results.

作者信息

Kopf G S, Hellenbrand W, Kleinman C, Lister G, Talner N, Laks H

出版信息

Ann Thorac Surg. 1986 Apr;41(4):425-30. doi: 10.1016/s0003-4975(10)62701-4.

DOI:10.1016/s0003-4975(10)62701-4
PMID:3963920
Abstract

The optimum surgical procedure for treatment of coarctation of the aorta in the neonatal period remains controversial. To assess immediate and long-term results of using primarily the subclavian flap angioplasty procedure (SFA), we reviewed our initial 5-year experience. The average follow-up was 6 years. From 1977 to 1981, 25 infants under 3 months of age (1 to 86 days, mean 21) required emergency surgery for repair of coarctation of the aorta. Three groups of patients were identified. Group I consisted of 10 patients with or without patent ductus arteriosus. In group II, 10 patients had coarctation association with one or multiple ventricular septal defects (VSDs) without other congenital defects. In group III, 5 patients had coarctation associated with more complex congenital heart lesions. Twenty-three SFAs and two patch aortoplasties were performed. No patient with isolated VSD was banded. All patients except one in group III with an associated atrioventricular canal survived initial hospitalizations. Four late deaths occurred, all in patients with associated complex heart defects. There were three recurrent coarctations requiring surgery or balloon angioplasty (12%)--one in each group, with a total rate of 0.77 recurrences per 100 patient-months. SFA for coarctation in the neonatal period is a safe and effective operation with a low initial mortality (4%, 0-19%, 70% confidence limits) well tolerated in this group of ill patients. Long-term outcome is primarily related to the presence of associated complex congenital defects. Infants with VSD associated with coarctation did not require pulmonary artery banding unless primary intracardiac repair was not feasible.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

新生儿期主动脉缩窄的最佳手术治疗方法仍存在争议。为评估主要采用锁骨下动脉瓣血管成形术(SFA)的近期和远期效果,我们回顾了最初5年的经验。平均随访时间为6年。1977年至1981年,25例3个月以下婴儿(1至86天,平均21天)因主动脉缩窄需要急诊手术修复。确定了三组患者。第一组包括10例有或无动脉导管未闭的患者。第二组,10例患者的主动脉缩窄合并一个或多个室间隔缺损(VSD),无其他先天性缺陷。第三组,5例患者的主动脉缩窄合并更复杂的先天性心脏病变。实施了23例SFA和2例补片主动脉成形术。没有对单纯VSD患者进行束带术。除第三组1例合并房室通道的患者外,所有患者均在首次住院期间存活。发生了4例晚期死亡,均为合并复杂心脏缺陷的患者。有3例复发性主动脉缩窄需要手术或球囊血管成形术(12%)——每组各1例,每100患者月的复发率为0.77。新生儿期主动脉缩窄的SFA是一种安全有效的手术,初始死亡率低(4%,0 - 19%,70%置信区间),在这组患病患者中耐受性良好。长期预后主要与合并复杂先天性缺陷的存在有关。合并主动脉缩窄的VSD婴儿,除非无法进行一期心内修复,否则不需要肺动脉束带术。(摘要截短至250字)

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