一种来自胡萝卜果实的新愈创木烷型倍半萜糖苷
One new guaiane-type sesquiterpene glycoside from the fruits of Daucus carota L.
作者信息
Fu Hong-Wei, Zhang Lin, Yi Tao, Feng Yu-Lin, Tian Jing-Kui
机构信息
College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, P. R. China.
出版信息
Pharmazie. 2010 Jan;65(1):69-71.
A new guaiane-type sesquiterpene glycoside, torilolone 8-O-beta-D-glucopyranoside (1), together with a known analogue compound, torilolone 11-O-beta-D-glucopyranoside (2), was isolated from the fruits of Daucus carota L. Their chemical structures were elucidated on the basis of MS, NMR spectroscopic analyses coupled with chemical degradation. The cytotoxic activities of two isolated compounds were evaluated against two human gastric cancer cell lines BGC-823 and AGS using MTT assay.
从胡萝卜（Daucus carota L.）果实中分离出一种新的愈创木烷型倍半萜糖苷，托里洛醇8 - O - β - D - 吡喃葡萄糖苷（1），以及一种已知的类似物化合物，托里洛醇11 - O - β - D - 吡喃葡萄糖苷（2）。通过质谱、核磁共振光谱分析以及化学降解确定了它们的化学结构。采用MTT法评估了这两种分离化合物对两种人胃癌细胞系BGC - 823和AGS的细胞毒性活性。
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