从胡萝卜(Daucus carota L.)果实中分离得到的两个新的瓜环型倍半萜
Two new guaiane-type sesquiterpenoids from the fruits of Daucus carota L.
机构信息
Department of Biomedical Engineering, Zhejiang University, The Key Laboratory of Biomedical Engineering of the Ministry of Education, Hangzhou, PR China.
出版信息
Fitoterapia. 2010 Jul;81(5):443-6. doi: 10.1016/j.fitote.2009.12.008. Epub 2010 Jan 11.
Two new guaiane-type sesquiterpenoids containing an interesting epoxy unit, daucuside (1) and daucusol (2) were isolated from the fruits of Daucus carota L. Their chemical structures were elucidated on the basis of MS, NMR spectroscopic analyses coupled with chemical degradation and they were also evaluated for the cytotoxic effects against two human gastric cancer cell lines BGC-823 and AGS.
从胡萝卜(Daucus carota L.)的果实中分离得到了两个新的愈创木烷型倍半萜类化合物，含有一个有趣的环氧单元，即胡萝卜苷(1)和胡萝卜醇(2)。基于 MS、NMR 谱分析结合化学降解，阐明了它们的化学结构，并评估了它们对两种人胃癌细胞系 BGC-823 和 AGS 的细胞毒性作用。
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