University of Zagreb, School of Medicine and University Hospital Centre Zagreb, Department of Neurology and Referral Center for Demyelinating Diseases of the Central Nervous System, Zagreb, Croatia.
Expert Rev Neurother. 2010 Mar;10(3):459-67. doi: 10.1586/ern.10.9.
Acute disseminated encephalomyelitis is an idiopathic inflammatory demyelinating disease of the CNS that is particularly difficult to differentiate from the first episode of multiple sclerosis, so called clinically isolated syndrome. Currently, no diagnostic criteria exist that could reliably differentiate these two diseases. More importantly no single clinical, neuroimaging or cerebrospinal fluid feature defines a disorder with absolute certainty. This review will summarize clinical and paraclinical characteristics of acute disseminated encephalomyelitis in adults, with special emphasis on diagnostic imaging.
急性播散性脑脊髓炎是一种中枢神经系统特发性炎症性脱髓鞘疾病，与多发性硬化症的首次发作（所谓的临床孤立综合征）特别难以区分。目前，尚无可靠区分这两种疾病的诊断标准。更重要的是，没有任何单一的临床、神经影像学或脑脊液特征可以绝对确定一种疾病。本综述将总结成人急性播散性脑脊髓炎的临床和辅助检查特征，特别强调诊断影像学。
