• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种从视网膜图像中检测血管的新方法。

A novel method for blood vessel detection from retinal images.

机构信息

School of Biomedical Engineering, Capital Medical University, Beijing, China.

出版信息

Biomed Eng Online. 2010 Feb 28;9:14. doi: 10.1186/1475-925X-9-14.

DOI:10.1186/1475-925X-9-14
PMID:20187975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2838898/
Abstract

BACKGROUND

The morphological changes of the retinal blood vessels in retinal images are important indicators for diseases like diabetes, hypertension and glaucoma. Thus the accurate segmentation of blood vessel is of diagnostic value.

METHODS

In this paper, we present a novel method to segment retinal blood vessels to overcome the variations in contrast of large and thin vessels. This method uses adaptive local thresholding to produce a binary image then extract large connected components as large vessels. The residual fragments in the binary image including some thin vessel segments (or pixels), are classified by Support Vector Machine (SVM). The tracking growth is applied to the thin vessel segments to form the whole vascular network.

RESULTS

The proposed algorithm is tested on DRIVE database, and the average sensitivity is over 77% while the average accuracy reaches 93.2%.

CONCLUSIONS

In this paper, we distinguish large vessels by adaptive local thresholding for their good contrast. Then identify some thin vessel segments with bad contrast by SVM, which can be lengthened by tracking. This proposed method can avoid heavy computation and manual intervention.

摘要

背景

视网膜图像中视网膜血管的形态变化是糖尿病、高血压和青光眼等疾病的重要指标。因此,血管的准确分割具有诊断价值。

方法

本文提出了一种新的方法来分割视网膜血管,以克服大而细的血管对比度的变化。该方法使用自适应局部阈值化生成二值图像,然后提取大的连通分量作为大血管。二值图像中的残余碎片包括一些细的血管段(或像素),通过支持向量机(SVM)进行分类。跟踪生长应用于细的血管段以形成整个血管网络。

结果

该算法在 DRIVE 数据库上进行了测试,平均灵敏度超过 77%,平均准确率达到 93.2%。

结论

本文通过自适应局部阈值化来区分对比度好的大血管,然后通过 SVM 识别一些对比度差的细血管段,这些段可以通过跟踪来延长。该方法可以避免大量的计算和人工干预。

相似文献

1
A novel method for blood vessel detection from retinal images.一种从视网膜图像中检测血管的新方法。
Biomed Eng Online. 2010 Feb 28;9:14. doi: 10.1186/1475-925X-9-14.
2
Segmentation of retinal blood vessels by combining the detection of centerlines and morphological reconstruction.通过结合中心线检测和形态学重建对视网膜血管进行分割。
IEEE Trans Med Imaging. 2006 Sep;25(9):1200-13. doi: 10.1109/tmi.2006.879955.
3
Retinal blood vessel segmentation using line operators and support vector classification.使用线算子和支持向量分类的视网膜血管分割
IEEE Trans Med Imaging. 2007 Oct;26(10):1357-65. doi: 10.1109/TMI.2007.898551.
4
A novel vessel segmentation algorithm for pathological retina images based on the divergence of vector fields.一种基于向量场散度的病理性视网膜图像血管分割新算法。
IEEE Trans Med Imaging. 2008 Feb;27(2):237-46. doi: 10.1109/TMI.2007.909827.
5
Automated characterization of blood vessels as arteries and veins in retinal images.视网膜图像中血管的自动分类为动脉和静脉。
Comput Med Imaging Graph. 2013 Oct-Dec;37(7-8):607-17. doi: 10.1016/j.compmedimag.2013.06.003. Epub 2013 Jul 10.
6
Texton-based segmentation of retinal vessels.基于纹理单元的视网膜血管分割
J Opt Soc Am A Opt Image Sci Vis. 2007 May;24(5):1384-93. doi: 10.1364/josaa.24.001384.
7
Segmentation of blood vessels from red-free and fluorescein retinal images.从无赤光和荧光素视网膜图像中分割血管。
Med Image Anal. 2007 Feb;11(1):47-61. doi: 10.1016/j.media.2006.11.004. Epub 2007 Jan 3.
8
Learning fully-connected CRFs for blood vessel segmentation in retinal images.学习用于视网膜图像血管分割的全连接条件随机场
Med Image Comput Comput Assist Interv. 2014;17(Pt 1):634-41. doi: 10.1007/978-3-319-10404-1_79.
9
A self-calibrating approach for the segmentation of retinal vessels by template matching and contour reconstruction.基于模板匹配和轮廓重建的视网膜血管自动分割方法。
Med Image Anal. 2016 Apr;29:24-46. doi: 10.1016/j.media.2015.12.003. Epub 2015 Dec 19.
10
A novel method for the automatic grading of retinal vessel tortuosity.一种用于视网膜血管迂曲度自动分级的新方法。
IEEE Trans Med Imaging. 2008 Mar;27(3):310-9. doi: 10.1109/TMI.2007.904657.

引用本文的文献

1
An Approach to Automatic Hard Exudate Detection in Retina Color Images by a Telemedicine System Based on the d-Eye Sensor and Image Processing Algorithms.基于 d-Eye 传感器和图像处理算法的远程医疗系统自动检测视网膜彩色图像中硬性渗出物的方法。
Sensors (Basel). 2019 Feb 8;19(3):695. doi: 10.3390/s19030695.
2
A robust technique based on VLM and Frangi filter for retinal vessel extraction and denoising.一种基于可变局部均值(VLM)和弗朗吉(Frangi)滤波器的用于视网膜血管提取和去噪的稳健技术。
PLoS One. 2018 Feb 12;13(2):e0192203. doi: 10.1371/journal.pone.0192203. eCollection 2018.
3
Blood Vessel Extraction in Color Retinal Fundus Images with Enhancement Filtering and Unsupervised Classification.

本文引用的文献

1
Retinal blood vessel segmentation using line operators and support vector classification.使用线算子和支持向量分类的视网膜血管分割
IEEE Trans Med Imaging. 2007 Oct;26(10):1357-65. doi: 10.1109/TMI.2007.898551.
2
An improved algorithm for vessel centerline tracking in coronary angiograms.一种用于冠状动脉血管造影中血管中心线跟踪的改进算法。
Comput Methods Programs Biomed. 2007 Nov;88(2):131-43. doi: 10.1016/j.cmpb.2007.08.004. Epub 2007 Oct 4.
3
Segmentation of blood vessels from red-free and fluorescein retinal images.从无赤光和荧光素视网膜图像中分割血管。
基于增强滤波和无监督分类的彩色眼底图像血管提取。
J Healthc Eng. 2017;2017:4897258. doi: 10.1155/2017/4897258. Epub 2017 Aug 3.
4
DR HAGIS-a fundus image database for the automatic extraction of retinal surface vessels from diabetic patients.DR HAGIS——一个用于从糖尿病患者眼底图像中自动提取视网膜表面血管的数据库。
J Med Imaging (Bellingham). 2017 Jan;4(1):014503. doi: 10.1117/1.JMI.4.1.014503. Epub 2017 Feb 9.
5
A Morphological Hessian Based Approach for Retinal Blood Vessels Segmentation and Denoising Using Region Based Otsu Thresholding.一种基于形态学黑塞矩阵的方法,用于使用基于区域的大津阈值法进行视网膜血管分割和去噪。
PLoS One. 2016 Jul 21;11(7):e0158996. doi: 10.1371/journal.pone.0158996. eCollection 2016.
6
Extraction of Blood Vessels in Retinal Images Using Four Different Techniques.使用四种不同技术提取视网膜图像中的血管
J Med Eng. 2013;2013:408120. doi: 10.1155/2013/408120. Epub 2013 Dec 17.
7
Retinal blood vessels extraction using probabilistic modelling.利用概率建模提取视网膜血管。
Health Inf Sci Syst. 2014 Jan 27;2:2. doi: 10.1186/2047-2501-2-2. eCollection 2014.
8
Comparative study of retinal vessel segmentation based on global thresholding techniques.基于全局阈值技术的视网膜血管分割比较研究
Comput Math Methods Med. 2015;2015:895267. doi: 10.1155/2015/895267. Epub 2015 Feb 22.
Med Image Anal. 2007 Feb;11(1):47-61. doi: 10.1016/j.media.2006.11.004. Epub 2007 Jan 3.
4
Retinal vessel segmentation using the 2-D Gabor wavelet and supervised classification.使用二维伽柏小波和监督分类进行视网膜血管分割。
IEEE Trans Med Imaging. 2006 Sep;25(9):1214-22. doi: 10.1109/tmi.2006.879967.
5
Segmentation of retinal blood vessels by combining the detection of centerlines and morphological reconstruction.通过结合中心线检测和形态学重建对视网膜血管进行分割。
IEEE Trans Med Imaging. 2006 Sep;25(9):1200-13. doi: 10.1109/tmi.2006.879955.
6
An improved matched filter for blood vessel detection of digital retinal images.一种用于数字视网膜图像血管检测的改进型匹配滤波器。
Comput Biol Med. 2007 Feb;37(2):262-7. doi: 10.1016/j.compbiomed.2006.03.003. Epub 2006 May 12.
7
Image registration and subtraction for the visualization of change in diabetic retinopathy screening.用于糖尿病视网膜病变筛查变化可视化的图像配准与减法运算。
Comput Med Imaging Graph. 2006 Apr;30(3):139-45. doi: 10.1016/j.compmedimag.2006.01.002. Epub 2006 May 2.