Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, 2525 West End Avenue, Suite 600, IMPH, Nashville TN 37203-1738, USA.
Br J Nutr. 2010 Jul;104(2):265-75. doi: 10.1017/S0007114510000383. Epub 2010 Mar 1.
The prevalence of hypertension has increased over the past decade in many developed and developing countries, including China. This increase may be associated with changes in lifestyle, including dietary patterns. We evaluated the association of dietary patterns with blood pressure (BP) by using data from a large, population-based cohort study of middle-aged and elderly Chinese men, the Shanghai Men's Health Study. The present cross-sectional analysis includes 39 252 men who reported no prior history of hypertension, diabetes, CHD, or stroke nor use of antihypertensive drugs at study enrolment. Three dietary patterns, 'vegetable', 'fruit and milk' and 'meat', were derived using factor analysis. The fruit and milk diet was inversely associated with both systolic and diastolic BP (Ptrend < 0.001). The adjusted mean systolic BP was 2.9 mmHg lower (95 % CI - 3.4, - 2.4), and diastolic BP was 1.7 mmHg lower (95 % CI - 2.0, - 1.4) for men in the highest quintile of the 'fruit and milk' pattern compared with men in the lowest quintile. This inverse association was more evident among heavy drinkers; the highest quintile of the 'fruit and milk' pattern was associated with a 4.1 mmHg reduction in systolic BP v. a 2.0 mmHg reduction among non-drinkers (Pinteraction = 0.003) compared to the lowest quintile. The corresponding reductions in diastolic BP were 2.0 v. 1.3 mmHg (Pinteraction = 0.011). The 'fruit and milk' pattern was associated with a lower prevalence of both pre-hypertension and hypertension, and the associations appeared to be stronger among drinkers. Results of the present study suggest an important role for diet in the prevention of hypertension.
在过去的十年中,包括中国在内的许多发达国家和发展中国家的高血压患病率都有所上升。这种增加可能与生活方式的改变有关,包括饮食模式。我们使用来自中国中老年男性大型人群队列研究的资料评估了饮食模式与血压(BP)之间的关联,该研究为上海男性健康研究。本横断面分析包括 39252 名男性,他们在研究入组时报告没有高血压、糖尿病、冠心病或中风病史,也没有服用抗高血压药物。使用因子分析得出三种饮食模式,“蔬菜”、“水果和牛奶”和“肉类”。水果和牛奶饮食与收缩压和舒张压均呈负相关(Ptrend<0.001)。与最低五分位数的男性相比,最高五分位数的“水果和牛奶”模式的男性收缩压平均降低 2.9mmHg(95%CI-3.4,-2.4),舒张压降低 1.7mmHg(95%CI-2.0,-1.4)。这种负相关在大量饮酒者中更为明显;与最低五分位数的男性相比,“水果和牛奶”模式的最高五分位数与收缩压降低 4.1mmHg 相关,而不饮酒者降低 2.0mmHg(P 交互=0.003),舒张压降低 2.0mmHg 与 1.3mmHg(P 交互=0.011)。“水果和牛奶”模式与高血压前期和高血压的患病率降低相关,且这种关联在饮酒者中似乎更强。本研究的结果表明饮食在预防高血压方面具有重要作用。